Objective: To report a case of successful paternity from a male homozygous for 5α-reductase-2 deficiency.
Design: Case report.
Setting: Academic center, division of reproductive endocrinology.
Patient(s): A 45-year-old Dominican man and his 32-year-old wife.
Intervention(s): In vitro fertilization and intracytoplasmic sperm injection.
Main Outcome Measure(s): Pregnancy.
Result(s): Viable twin gestation.
Conclusion(s): Men homozygous for 5α-reductase-2 deficiency can achieve biologic paternity through in vitro fertilization with intracytoplasmic sperm injection despite severely abnormal semen parameters.
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| http://dx.doi.org/10.1016/j.fertnstert.2011.01.121 | DOI Listing |
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