Advances of bioinformatics tools applied in virus epitopes prediction.

Virol Sin

State Key Laboratory of Virology, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, 430071, China.

Published: February 2011

In recent years, the in silico epitopes prediction tools have facilitated the progress of vaccines development significantly and many have been applied to predict epitopes in viruses successfully. Herein, a general overview of different tools currently available, including T cell and B cell epitopes prediction tools, is presented. And the principles of different prediction algorithms are reviewed briefly. Finally, several examples are present to illustrate the application of the prediction tools.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7090880PMC
http://dx.doi.org/10.1007/s12250-011-3159-4DOI Listing

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