The photodynamic action of a number of carboxylic porphyrins and their covalent conjugates with specific monoclonal IgM antibodies on a human lung adenocarcinoma cell line was studied. All the conjugates showed strong phototoxicity which did not correspond with the phototoxicity of the free porphyrins. Absolute quantum yields of singlet oxygen photogeneration by the porphyrins and their conjugates were obtained and compared with the phototoxicity of the compounds.
Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
porphyrins conjugates
8
conjugates specific
8
photodestruction vitro
4
vitro tumour
4
tumour cells
4
cells sensitized
4
porphyrins
4
sensitized porphyrins
4
conjugates
4
specific antibodies
4
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!