Background: The incidence of penetrating abdominal injuries (PAI) has increased in the West African sub-region.
Objective: To determine the pattern and management outcome of penetrating abdominal injuries (PAI) in the two main teaching hospitals in Ghana.
Study Design: A prospective and retrospective descriptive study.
Setting: Komfo Anokye Teaching Hospital (KATH), Kumasi and Korle-Bu Teaching Hospital (KBTH), Accra.
Methods: Relevant details of all adult patients admitted with penetrating abdominal injuries over a 11-year period were recorded at KATH and KBTH in Accra. The study in KATH was prospective pro forma based and that in the KBTH was a retrospective case review of all penetrating abdominal injuries.
Results: There were 411 patients, mostly men (M: F-8:1). The peak age of patients was 20-29 years, 164 patients (39.9%). Abdominal stab wound injuries accounted for 251 (61.1%). Three hundred and thirty - one patients (80.5%) had an emergency laparotomy. Twelve patients required 16 emergency thoracotomies. The small bowel (23.2%), stomach (12.9%), colon (10.2%), the liver (10.0%), were the most commonly injured organs. In 92 patients (29.0%) no significant intra-abdominal injury was detected at laparotomy
Conclusion: Stab wounds are the main penetrating abdominal injuries seen mostly among young male adults in Ghana. Management was by a mandatory laparotomy after clinical assessment. The overall mortality was 4.4%. Selective non-operative management of abdominal stab wounds is possible.
Download full-text PDF |
Source |
---|---|
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2996836 | PMC |
http://dx.doi.org/10.4314/gmj.v44i3.68893 | DOI Listing |
Diagnostics (Basel)
March 2025
Department of Surgery I, "Grigore T. Popa" University of Medicine and Pharmacy, 700115 Iași, Romania.
Despite advancements in prevention and treatment, peptic ulcer disease (PUD) remains a public health burden, with potentially high mortality rates when not managed properly. Recent studies indicate bleeding as the most prevalent complication, followed by perforation or penetration into adjacent organs and pyloric obstruction. In rare cases, posterior wall or greater curvature ulcers of the stomach can penetrate, leading to splenic artery pseudoaneurysms.
View Article and Find Full Text PDFEur J Med Chem
March 2025
State Key Laboratory of Trauma and Chemical Poisoning, Institute of Combined Injury of PLA, College of Preventive Medicine, Army Medical University, Chongqing, 400038, China. Electronic address:
The increasing infections caused by carbapenem-resistant Acinetobacter baumannii (CRAB) poses a serious threat to global public health. Antimicrobial peptides (AMPs) are alternatives to conventional antibiotics in combating superbugs. However, discovering AMPs with low synthesis costs and strong antibacterial effects against CRAB is challenging.
View Article and Find Full Text PDFCureus
February 2025
Anaesthesiology, All India Institute of Medical Sciences, New Delhi, IND.
Airway management in trauma patients is a critical component of resuscitation, often complicated by the unique positioning required by the nature and location of injuries. Penetrating abdominal trauma requiring lateral positioning presents an uncommon and challenging scenario for airway stabilization, particularly when traditional supine approaches are contraindicated. We describe the case of an 18-year-old male patient who was taken to the operating theater with a penetrating abdominal injury necessitating lateral positioning due to ongoing bleeding and hemodynamic instability.
View Article and Find Full Text PDFJ Surg Case Rep
February 2025
Department of Surgery, Nara Medical University 840 Shijo-cho, Kashihara, Nara, Japan.
Management of gastrointestinal perforation in patients with vascular Ehlers-Danlos syndrome (vEDS) is clinically challenging. A male in his 40s with vEDS presented with right lower abdominal pain. Computed tomography revealed a foreign body in the ileum with bowel perforation.
View Article and Find Full Text PDFMol Cell Biochem
March 2025
School of Pharmacy and Technology Management, SVKM's Narsee Monjee Institute of Management Studies (NMIMS), Deemed-to-University, Green Industrial Park, TSIIC, Polepally, Jadcherla, Hyderabad, Telangana, 509301, India.
Emerging evidence indicates that chloride channels (ClCs) significantly affect the pathogenesis of inflammatory bowel disease (IBD) through their regulatory roles in mast cell function and epithelial integrity. IBD, encompassing conditions such as Crohn's disease and ulcerative colitis, involves chronic inflammation of the gastrointestinal tract, where channels influence immune responses, fluid balance, and cellular signalling pathways essential for maintaining mucosal homeostasis. This review examines the specific roles of ClC in mast cells, focussing on the regulation of mast cell activation, degranulation, cytokine release, and immune cell recruitment in inflamed tissues.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!