The general transcription factor TFIIB plays essential, but as yet unclear, roles in transcription initiation by RNA polymerase II. We recently found that phosphorylation of TFIIB is required for productive transcription. We discuss the implications of this work for the functions of TFIIB in promoter escape and gene loop formation.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3023571 | PMC |
| http://dx.doi.org/10.4161/trns.1.3.12900 | DOI Listing |
Publication Analysis
Top Keywords
transcription initiation
8
insights role
4
tfiib
4
role tfiib
4
transcription
4
tfiib transcription
4
initiation general
4
general transcription
4
transcription factor
4
factor tfiib
4
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!