The autopsy and histopathological changes in the wall of aortic arch were presented in calves died of pulmonary and intestinal disorders. The bacteriological examinations of the internal organs demonstrated: E. coli, Pseudomonas aeruginosa Corynebacterium et al. Gelatinous edematous++ and hemorrhagic inflammatory centers of aortic arch adventitia were distinctly visible during thorax examination. In aortic arch the diagonal fissures of endothelium and deeper layers of the wall were found. In microscopical examination the heavy degenerative changes in the arch endothelium and deeper layers were observed. The fissures were from 0.5 to several millimeters in length and penetrated 1/3 to 1/2 thickness at the wall. The authors suggested that starting point of this changes are Gram-negative bacillary inflammatory centers in lungs. The bacterial endotoxins and vasoactive substances liberated by altered cells penetrated the aortic arch by the tissues continuity and in contact way.
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