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Recurrent Aseptic (Mollaret) Meningitis: A Case Report.
Cureus
October 2024
Emergency Medicine, Veterans Affairs Medical Center, Prescott, USA.
Mollaret meningitis is a rare form of recurrent, self-resolving, aseptic meningitis with a high rate of return. Although it has been associated with several conditions, herpes simplex virus type 2 (HSV-2) is most common. Diagnosis requires recurrent (>3) episodes of aseptic meningitis as defined by pleocytosis in cerebrospinal fluid (CSF) with negative bacterial cultures.
View Article and Find Full Text PDFA patient with P369S/R408Q variants in the MEFV gene presented with clinical features of Kikuchi disease and Mollaret meningitis, successfully treated with colchicine.
BMC Neurol
November 2024
Department of Neurology, Graduate School of Medicine, Chiba University, 1-8-1 Inohana, Chuo-ku, Chiba, 260-8677, Japan.
Article Synopsis
- A 41-year-old Japanese woman with MEFV gene mutations presented with symptoms of Kikuchi disease and Mollaret meningitis, including fever, headache, and cervical lymphadenopathy.
- Diagnostic tests confirmed Kikuchi disease through a lymph node biopsy and identified increased lymphocytes and three pathognomonic Mollaret cells in her cerebrospinal fluid.
- Treatment with colchicine effectively managed her recurrent episodes of Kikuchi disease and meningitis, suggesting colchicine may be a viable option for similar cases.
An Anterior Midline Skull Base Epidermoid Cyst Presenting With Spontaneous Intraparenchymal Rupture: A Case Report.
Cureus
September 2024
Neurosurgery, University of Louisville, Louisville, USA.
Article Synopsis
- Intracranial epidermoid cysts (ECs) are uncommon, non-cancerous growths usually located in specific areas of the brain, and they typically develop from leftover ectodermal cells from embryology.
- Although these cysts are present from birth, symptoms usually appear in middle age due to pressure effects on surrounding brain tissue.
- The case presented involves a 69-year-old man with an EC that unexpectedly ruptured and impacted brain tissue, highlighting a rare occurrence and contributing new insights to the understanding of these cysts.
Mollaret's Meningitis due to Herpes Simplex Virus 2: A Case Report and Review of the Literature.
Microorganisms
July 2024
Microbiology Unit, IRCCS Azienda Ospedaliero-Universitaria di Bologna, 40138 Bologna, Italy.
Mollaret's meningitis is a rare neurological disorder characterized by recurrent episodes of aseptic lymphocytic meningitis, often associated with herpes simplex virus 2 (HSV-2) infection. We report the case of a 39 y.o.
View Article and Find Full Text PDFBenign recurrent lymphocytic meningitis (Mollaret's meningitis) in Denmark: a nationwide cohort study.
Eur J Neurol
January 2024
Department of Medicine, Zealand University Hospital, Roskilde, Denmark.
Background And Purpose: Data on clinical features and outcomes of benign recurrent lymphocytic meningitis (BRLM) are limited.
Methods: This was a nationwide population-based cohort study of all adults hospitalized for BRLM associated with herpes simplex virus type 2 (HSV-2) at the departments of infectious diseases in Denmark from 2015 to 2020. Patients with single-episode HSV-2 meningitis were included for comparison.
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