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http://dx.doi.org/10.1093/bioinformatics/btr071 | DOI Listing |
The kinetically-derived maximal dose (KMD) is defined as the maximum external dose at which kinetics are unchanged relative to lower doses, e.g., doses at which kinetic processes are not saturated.
View Article and Find Full Text PDFNeuropsychiatr Dis Treat
December 2024
School of Health and Biomedical Sciences, RMIT University, Bundoora, VIC, 3083, Australia.
J Appl Stat
June 2024
Department of Statistical Sciences, University of Toronto, Toronto, ON, Canada.
We propose a model for multiple waves of an epidemic that decomposes the health outcome of interest into the sum of scaled skew normal curves. When applied to daily COVID-19 mortality in six regions (Japan, Italy, Belgium, Ontario, Texas, and Peru), this model provides three notable results. First, when fit to data from early 2020 to May 31, 2022, the estimated skew normal curves substantially overlap with the dates of COVID-19 waves in Ontario and Belgium, as determined by their respective health authorities.
View Article and Find Full Text PDFNeuropsychiatr Dis Treat
November 2024
Hangzhou Third Hospital Affiliated to Zhejiang Chinese Medical University, Hangzhou, Zhejiang, People's Republic of China.
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