The primary aim of this study was to validate the saccadic main sequence, in particular the peak velocity [PV], as an alternative psychophysiological measure of Mental Workload [MW]. Taking the Wickens' multiple resource model as the theoretical framework of reference, an experiment was conducted using the Firechief® microworld. MW was manipulated by changing the task complexity (between groups) and the amount of training (within groups). There were significant effects on PV from both factors. These results provide additional empirical support for the sensitivity of PV to discriminate MW variation on visual-dynamic complex tasks. These findings and other recent results on PV could provide important information for the development of a new vigilance screening tool for the prevention of accidents in several fields of applied ergonomics.
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http://dx.doi.org/10.1016/j.apergo.2011.01.003 | DOI Listing |
Trends Genet
January 2025
Institute for Computational Genomic Medicine, Goethe University Frankfurt, Frankfurt, Germany; German Centre for Cardiovascular Research (DZHK), Partner Site Rhine-Main, Frankfurt, Germany. Electronic address:
MicroRNAs (miRNAs) are key regulators of gene expression and control cellular functions in physiological and pathophysiological states. miRNAs play important roles in disease, stress, and development, and are now being investigated for therapeutic approaches. Alternative processing of miRNAs during biogenesis results in the generation of miRNA isoforms (isomiRs) which further diversify miRNA gene regulation.
View Article and Find Full Text PDFInt J Pediatr Otorhinolaryngol
January 2025
Dr. Elie E. Rebeiz Department of Otolaryngology - Head and Neck Surgery, Tufts Medical Center, Boston, MA, USA. Electronic address:
Background: Internal and external devices may be utilized in mandibular distraction osteogenesis (MDO) for the correction of symptomatic micrognathia in infants and children.
Purpose: To compare the rate and severity of infection between internal and external MDO devices.
Study Design, Setting, Sample: Retrospective cohort study utilizing an institutional database of patients who underwent MDO.
Cortex
December 2024
Humboldt-Universität zu Berlin, Berlin School of Mind and Brain, Berlin, Germany; Max Planck Institute for Human Cognitive and Brain Sciences, Department of Neurology, Leipzig, Germany; University Hospital and Faculty of Medicine Leipzig, Clinic for Cognitive Neurology, Leipzig, Germany.
Retrieving words quickly and correctly is an important language competence. Semantic contexts, such as prior naming of categorically related objects, can induce conceptual priming but also lexical-semantic interference, the latter likely due to enhanced competition during lexical selection. In the continuous naming (CN) paradigm, such semantic interference is evident in a linear increase in naming latency with each additional member of a category out of a seemingly random sequence of pictures being named (cumulative semantic interference/CSI effect).
View Article and Find Full Text PDFSyst Biol Reprod Med
December 2025
Department of Biosciences and Technology for Food, Agriculture and Environment, University of Teramo, Teramo, Italy.
MicroRNAs (miRNAs) have acquired an increased recognition to unravel the complex molecular mechanisms underlying Diminished Ovarian Reserve (DOR), one of the main responsible for infertility. To investigate the impact of miRNA profiles in granulosa cells and follicular fluid, crucial players in follicle development, this study employed a computational network theory approach to reconstruct potential pathways regulated by miRNAs in granulosa cells and follicular fluid of women suffering from DOR. Available data from published research were collected to create the FGC_MiRNome_MC, a representation of miRNA target genes and their interactions.
View Article and Find Full Text PDFViruses
January 2025
Research Center for Life Sciences Computing, Zhejiang Lab, Hangzhou 311100, China.
, a medicinal herbaceous plant documented in the Chinese Pharmacopoeia, is a promising candidate for research into plant-derived pharmaceuticals. However, the study of newly emerging viruses that threaten the cultivation of remains limited. In this study, plants exhibiting symptoms such as leaf yellowing, mottled leaves, and vein chlorosis were collected and subjected to RNA sequencing to identify potential viral pathogens.
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