AI Article Synopsis
- Whole grain cereals are a rich source of lignans, which are compounds linked to potential health benefits such as anti-cancer and antioxidant properties.
- A new method was developed to analyze lignans in wheat bran using gas chromatography with electron capture detection, improving sensitivity and detection limits.
- The method demonstrated good accuracy and is a more cost-effective alternative to traditional liquid chromatography techniques, making lignan analysis easier and more accessible.
Article Abstract
Whole grain cereals are an important source of bioavailable lignans, the group of compounds with potential anti-cancerogenic, antioxidant, anti-proliferative, pro-apoptotic, and antiangiogenic properties. The aim of this work was to develop a sensitive method for determination of wheat bran lignans. The analysis of lignans secoisolariciresinol, hydroxymatairesinol, lariciresinol, matairesinol, pinoresinol, syringaresinol is based on derivatization with pentafluoropropionic anhydride (PFPA) and gas chromatography-electron capture detection (GC-ECD), using styrene glycol as internal standard. To our knowledge, this is the first time that EC detection has been used for lignan analysis. The results show that the technique is reproducible and sensitive enough for detecting lignans in wheat at parts-per-billion (ppb) levels, except for hydroxymatairesinol. The method developed showed good recovery (85-105%) and precision (4-20%) for five types of lignans and thus represents a simpler and more affordable alternative to state-of-the-art wheat lignan liquid chromatography tandem mass spectrometry (LC-MS/MS) analysis.
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| http://dx.doi.org/10.1016/j.talanta.2010.12.025 | DOI Listing |
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