A platform capable of seamlessly unifying both optoelectrowetting and optoelectronic tweezers is presented. This enables the user to manipulate aqueous droplets (with electrowetting) as well as individual particles within those droplets (with dielectrophoresis). The device requires no photolithography and droplet/particle manipulation can occur continuously over the entire surface of the device. Droplet and 10 µm polystyrene particle speeds of up to 8 mm s(-1) and 60 µm s(-1), respectively, are demonstrated. Particle concentration within, and subsequent splitting of, a droplet is performed resulting in average concentration efficiencies of 93%. Serial concentration is also demonstrated resulting in exponentially increasing particle concentrations and a 10× concentration increase. Finally, the platform is used to select a single cell out of a cohort and subsequently encapsulate it in its own aqueous droplet.
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http://dx.doi.org/10.1039/c0lc00568a | DOI Listing |
Electrophoresis
August 2024
School of Mechanical and Electrical Engineering, Hainan University, Haikou, Hainan, P. R. China.
To explore the optoelectronic wetting droplet transport mechanism, a transient numerical model of optoelectrowetting (OEW) under the coupling of flow and electric fields is established. The study investigates the impact of externally applied voltage, dielectric constant of the dielectric layer, and interfacial tension between the two phases on the dynamic behavior of droplets during transport. The proposed model employs an improved Young's equation to calculate the instantaneous voltage and contact angle of the droplet on the dielectric layer.
View Article and Find Full Text PDFInt J Anal Chem
May 2022
Integrated Optoelectronics and Microoptics Research Group, Physics Department, Technische Universität Kaiserslautern (TUK), PO Box 3049, D-67653, Kaiserslautern, Germany.
Electrically conducting liquid droplets can be activated and moved by electrowetting-on-dielectric (EWOD) and optoelectrowetting (OEW). An important application is droplet manipulation in digital microfluidics (DMF, lab-on-a-chip 2.0) as a chip-sized chemical laboratory.
View Article and Find Full Text PDFInt J Anal Chem
December 2021
Integrated Optoelectronics and Micro Optics Research Group, Physics Department, Technische Universität Kaiserslautern (TUK), P.O. Box 3049, Kaiserslautern D-67653, Germany.
Meanwhile, electrowetting-on-dielectric (EWOD) is a well-known phenomenon, even often exploited in active micro-optics to change the curvature of microdroplet lenses or in analytical chemistry with digital microfluidics (DMF, lab on a chip 2.0) to move/actuate microdroplets. Optoelectrowetting (OEW) can bring more flexibility to DMF because in OEW, the operating point of the lab chip is locally controlled by a beam of light, usually impinging onto the chip perpendicularly.
View Article and Find Full Text PDFLab Chip
April 2011
Berkeley Sensor and Actuator Center, Department of Electrical Engineering and Computer Science, University of California Berkeley, 497 Cory Hall, Berkeley, CA 94720, USA.
A platform capable of seamlessly unifying both optoelectrowetting and optoelectronic tweezers is presented. This enables the user to manipulate aqueous droplets (with electrowetting) as well as individual particles within those droplets (with dielectrophoresis). The device requires no photolithography and droplet/particle manipulation can occur continuously over the entire surface of the device.
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