This paper reports the compact synthesis of two isomeric dual-action hybrid antimicrobials where the 13-position of the antibacterial berberine has been linked via 3'- and 4'-methylene bridges to INF55 (5-nitro-2-phenylindole), an inhibitor of the bacterial NorA multidrug-resistance pump.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3035389 | PMC |
| http://dx.doi.org/10.1080/00397910903457415 | DOI Listing |
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