Objectives: The primary objective was to determine the erosive effect of expectorated saliva, following chewing acidic gum, on enamel and dentine samples, using a non-acidic gum as a negative control. Secondary objectives were to determine the effect of brushing enamel and dentine samples and the effect of individual saliva pH and buffering.
Design: A single-centre, single-blind, placebo-controlled, two-way crossover study.
Setting: A clinical trial, involving healthy participants, undertaken at Bristol Dental School and Hospital.
Methods: Eight healthy participants expectorated saliva onto prepared enamel and dentine samples while chewing gum (strawberry flavoured acidic gum [active] or peppermint flavoured non-acidic gum [control]). Half of the enamel and dentine samples were brushed before measurement by contact profilometry.
Main Outcome Measures: Mean enamel and dentine erosion, with and without brushing and the relationship to salivary buffering.Results At 10 days, mean depth of surface loss from dentine samples (95% CI), following chewing of acid-containing gum and subsequent brushing, was -11.34 μm (2.22 μm) and from un-brushed dentine samples was -11.02 μm (1.71 μm). No significant erosion was noted for other groups.
Conclusions: Frequent chewers of acid-containing gums are susceptible to dentine erosion even in the presence of good salivary buffering. Enamel erosion was insignificant within the time constraints of the present study but warrants further investigation.
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http://dx.doi.org/10.1038/sj.bdj.2011.51 | DOI Listing |
JBMR Plus
February 2025
Division of Biosciences, College of Dentistry, The Ohio State University, Columbus, OH, 43210, United States.
Hypophosphatasia (HPP) is an inherited error in metabolism resulting from loss-of-function variants in the gene, which encodes tissue-nonspecific alkaline phosphatase (TNAP). TNAP plays a crucial role in biomineralization of bones and teeth, in part by reducing levels of inorganic pyrophosphate (PP), an inhibitor of biomineralization. HPP onset in childhood contributes to rickets, including growth plate defects and impaired growth.
View Article and Find Full Text PDFMater Today Bio
February 2025
State Key Laboratory for Modification of Chemical Fibers and Polymer Materials, College of Materials Science and Engineering, Donghua University, Shanghai, 201620, PR China.
Natural teeth fulfill functional demands by their heterogeneity. The composition and hydroxyapatite (HAp) nanostructured orientation of enamel differ from those of dentin. However, mimicking analogous materials still exhibit a significant challenge.
View Article and Find Full Text PDFLasers Med Sci
January 2025
School of Medicine and Dentistry, Griffith University, Gold Coast, QLD, Australia.
This in-vitro study assessed the influence of the shade of human teeth on the transmission of near-infrared light. A total of 40 teeth were used. After cleaning the root surface and removing cementum, the teeth were sectioned into slices 3 mm thick, with each comprising a portion of the crown (enamel-dentine (ED)) and of the root (dentine only).
View Article and Find Full Text PDFPolymers (Basel)
January 2025
Department of Materials and Applied Chemistry, College of Science and Technology, Nihon University, 1-8-14 Kandasurugadai, Chiyoda-ku, Tokyo 101-8308, Japan.
Calcified tissues in living organisms, such as bone, dentin, and enamel, often require surgical intervention for treatment. However, advances in regenerative medicine have increased the demand for materials to assist in regenerating these tissues. Among the various forms of calcium phosphate (CaP), tricalcium phosphate (TCP)-particularly its α-TCP form-stands out due to its high solubility and efficient calcium release, making it a promising candidate for bone regeneration applications.
View Article and Find Full Text PDFJ Clin Med
January 2025
Department of Oral Biology, Faculty of Dentistry, Naresuan University, Phitsanulok 65000, Thailand.
: Chemotherapy (CMT) in children can disrupt dental development and calcification, causing long-term dental issues, but good dental care and habits can help improve quality of life. This case report examines permanent dental disturbances in a 7-year, 4-month-old girl undergoing CMT, explores the histology of microdontia, and outlines an oral treatment plan for CMT management. : Clinical examination revealed microdontia and a groove crossing the cervical area (chronological hypoplasia), which were assessed using panoramic radiographs and histological analysis.
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