An analysis of an autonomous component of the pain syndrome has been performed in 484 patients with neck and head pain syndromes. The frequency of autonomous disorders in this cohort reaches 84,7%. Autonomous dysregulation in different nosological groups as assessed with the A.M. Vein questionnaire was seen in all types of pain syndromes but was most distinct in cases of migraine, cervicogenic headache, headache of tension and trigeminal neuropathy. The data obtained suggest the deficiency of brain regulatory mechanism functions responsible for adaptation of the organism to external and internal changes and explain, in large, signs of maladaptation in patients with cervicocranial pain syndromes. The use of vegetotropic drugs in the complex therapy of neck and head pain is pathogenetically substantiated.

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