Lewis acid activated synthesis of highly substituted cyclopentanes by the N-heterocyclic carbene catalyzed addition of homoenolate equivalents to unsaturated ketoesters.

Daniel T Cohen Benoit Cardinal-David Karl A Scheidt

Angew Chem Int Ed Engl

Department of Chemistry, Center for Molecular Innovation and Drug Discovery, Chemistry of Life Processes Institute, Northwestern University, 2145 Sheridan Road, Evanston, IL 60208, USA.

Published: February 2011

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3275665	PMC
http://dx.doi.org/10.1002/anie.201005908	DOI Listing

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