AI Article Synopsis
- Mucormycosis is a severe fungal infection that's becoming more common, especially in patients with gastrointestinal involvement, which tends to have a high mortality rate.
- A case study is presented of a patient who sustained gunshot wounds and developed mucormycosis in the abdominal area, requiring extensive surgical intervention and antifungal treatment.
- The patient ultimately survived the infection, showing the importance of considering mucormycosis in trauma patients with persistent infections, and emphasizing the need for aggressive treatment when diagnosed.
Article Abstract
Background: Mucormycosis is a deadly angioinvasive fungal infection that is increasing in incidence. Gastrointestinal and abdominal involvement is rare, has higher mortality rates, and is frequently diagnosed late.
Methods: We report a patient who sustained multiple gunshot wounds to the chest and abdomen and subsequently developed omental and hepatic mucormycosis. He underwent 14 abdominal washouts and several liver debridements, and he received combination therapy with amphotericin B and micafungin.
Results: The patient survived the disease, with negative cultures and pathology at the last washout, and underwent skin grafting. He is clinically improved and remains on oral antifungals as an outpatient.
Conclusions: Mucormycosis should be considered in trauma patients with persistent signs of infection after lavage and antibiotics, especially when necrosis or atypical wound presentations are noted. Approaches such as ours using aggressive surgical management and intensive antifungal administration should be instituted once the diagnosis is suspected.
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| http://dx.doi.org/10.1097/TA.0b013e31820784ff | DOI Listing |
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