An ethnobotanical survey was conducted on plants used traditionally for the management of tuberculosis in five local government areas of Ogun State, Nigeria, in a bid to document herbs used in the management of tuberculosis with the aim of identifying possible drug lead from the phytomedicine of these communities. A semi-structured questionnaire was used to obtain the required information on the use of herbal remedies for the management. A total of 50 respondents made up of herbalists (40.0%), herb sellers (52.0%) and traditional medicine practitioners (8.0%) were interviewed in the study. The dominant age of respondents was in the range of 21-40 years (72.0%). Duration of treatment of tuberculosis with herbs was between 2-12 weeks. A total of 36 plants belonging to 20 families were proffered for the management of tuberculosis. Eighty four percent (42%) of the 50 respondents interviewed said that their clients observed no side effects and that the herbs were either available in the forest or purchased from the markets. Cola acumminata (fruit), Garcinia kola (leaf), Vitallaria parodoxa (oil), Costus afer (stem), Pycnanthus angolensis (stem bark) and Aframomum melegueta (fruit) were the most frequently mentioned herbs. The ethnomedicines of the studied areas of Ogun State, Nigeria seem to have a high potential as a source of drug discovery of anti-tuberculosis. This is of utmost importance because people living with human immunodeficiency virus (HIV) are susceptible to tuberculosis.
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http://dx.doi.org/10.4314/ajtcam.v7i1.57270 | DOI Listing |
Zhonghua Yi Xue Za Zhi
February 2025
Neurobrucellosis is a neurological disorder caused by Brucella infection. It typically occurs as part of the multisystem involvement of brucellosis, or may also present as brucellosis. The existing clinical practice guidelines and expert consensus on human brucellosis are outdated and provide limited guidance specific to the diagnosis and management of neurobrucellosis, failing to meet the evolving needs of healthcare providers and patients.
View Article and Find Full Text PDFInt J Nurs Stud
January 2025
Johns Hopkins University Center for Infectious Disease and Nursing Innovation, Baltimore, MD, USA; Johns Hopkins University School of Nursing, Baltimore, MD, USA.
Introduction: Undetectable equals untransmittable (U=U) is an education campaign promoting science that people living with human immunodeficiency virus (HIV) who maintain an undetectable viral load cannot transmit HIV to others. Researchers theorize that undetectable equals untransmittable messaging will decrease HIV stigma by reducing fears of HIV transmission and providing evidence to dismantle discriminatory policies. However, little is known about how people with HIV in South Africa interpret the results of their viral load tests, undetectable equals untransmittable messaging, or its impact on stigma.
View Article and Find Full Text PDFBMJ Open
January 2025
Faculty of Health Sciences, Simon Fraser University, Burnaby, BC, Canada.
Introduction: Non-adherence to tuberculosis (TB) treatment poses a significant challenge to effective TB management globally and is a major contributor to the emergence of multidrug-resistant TB. Although adherence to TB treatment has been widely studied, a comprehensive evaluation of the comparative levels of adherence in high- versus low-TB burden settings remains lacking. The objective of this systematic review and meta-analysis is to assess the levels of adherence to TB treatment in high-TB burden countries compared to low-burden countries.
View Article and Find Full Text PDFFuture Sci OA
December 2025
Gastroenterology Department, La Rabta Hospital, Tunis, Tunisia.
Background: Colonic stenosis in Crohn's disease (CD) is uncommon, and data on surgery-free survival are limited. This study aimed to determine surgery-free survival rates and identify associated factors.
Patients And Methods: A retrospective study was conducted from 2003 to 2022, including patients with CD complicated by colonic stenosis.
Microorganisms
December 2024
Department of Laboratory Medicine, Korea University Anam Hospital, Korea University College of Medicine, Seoul 02841, Republic of Korea.
Background: Accurate and timely diagnosis of mycobacterial infections, including complex (MTBC) and nontuberculous mycobacteria (NTM), is crucial for effective disease management.
Methods: This study evaluated the performance of the NeoPlex TB/NTM-5 Detection Kit (NeoPlex assay, Seongnam, Republic of Korea), a multiplex real-time PCR assay that incorporates melting curve analysis, compared with the line-probe assay (LPA). The NeoPlex assay could simultaneously detect and differentiate MTBC from five other NTM species: , , , , and .
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