The creation of sialoliths in the ductal system of major salivary glands causes characteristic symptoms due to the obstruction of the flow of produced saliva. If sialolithiasis is not treated early obstructive sialadenitis will develop and its repeated relapses may lead to fibrosis and degeneration of glandular parenchyma. In this study we present the method of intraglandular injection of biotherapeutic solution (1.000.000 I.U. penicillin G in 5 cc normal saline) to achieve treatment of obstructive sialadenitis and rejection of the sialolith. Our results as shown in tables I and II and in figures 1-9 are very encouraging. From the conclusions drawn it looks like this method can be recommended as an optional solution to surgery (lithectomy-adenectomy) under the conditions mentioned in the discussion.
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Eur Arch Otorhinolaryngol
December 2024
Department of Otorhinolaryngology and Head- Neck Surgery, All India Institute of Medical Sciences, New Delhi, India.
Purpose: Orocervical (OCF) or pharyngocutaneous fistula (PCF) are one of the disastrous complications of head and neck cancer surgery. Conventional standards of management are predominantly conservative. Though a majority of such patients respond to conservative management, it nevertheless causes significant delay in wound healing.
View Article and Find Full Text PDFJ Laryngol Otol
November 2024
Department of Otolaryngology, Faculty of Medicine, Universiti Malaya, Lembah Pantai, 50603 Kuala Lumpur, Malaysia.
BMC Cancer
July 2024
ENT and Head and Neck Research Center and Department, The Five Senses Health Institute, School of Medicine, Iran University of Medical Sciences, Tehran, Iran.
Radiotherapy in patients with head and neck cancer fairly leads to xerostomia, profoundly affecting their quality of life. With limited effective preventive and therapeutic methods, attention has turned to exploring alternatives. This article outlines how intraglandular injection of mitochondria-boosting agents can serve as a potential strategy to reduce salivary acinar damage.
View Article and Find Full Text PDFFront Neurol
December 2023
Specialist Center for Pediatric Neurology, Neurorehabilitation and Epileptology, Schön Clinic, Vogtareuth, Germany.
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