The impact of part-time employment on adolescent functioning remains unclear because most studies fail to adequately control for differential selection into the workplace. The present study reanalyzes data from L. Steinberg, S. Fegley, and S. M. Dornbusch (1993) using multiple imputation, which minimizes bias in effect size estimation, and 2 types of propensity score matching, to account for selection effects. In this sample (N = 1,792; Grades 10-11, M = 16.26), youth who begin working more than 20 hr per week evince declines in school engagement and increases in substance use and delinquency compared with youth who remain unemployed. Conversely, working 20 hr or less a week has negligible effects, positive or negative, on academic, psychological, or behavioral outcomes.
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http://dx.doi.org/10.1111/j.1467-8624.2010.01543.x | DOI Listing |
Nat Commun
January 2025
MRC Laboratory of Medical Sciences, London, UK.
Gene enhancers often form long-range contacts with promoters, but it remains unclear if the activity of enhancers and their chromosomal contacts are mediated by the same DNA sequences and recruited factors. Here, we study the effects of expression quantitative trait loci (eQTLs) on enhancer activity and promoter contacts in primary monocytes isolated from 34 male individuals. Using eQTL-Capture Hi-C and a Bayesian approach considering both intra- and inter-individual variation, we initially detect 19 eQTLs associated with enhancer-eGene promoter contacts, most of which also associate with enhancer accessibility and activity.
View Article and Find Full Text PDFBiomedicines
December 2024
Department of Sports Science, RPTU University of Kaiserslautern-Landau, 67663 Kaiserslautern, Germany.
Patellofemoral pain (PFP) significantly affects patients' daily activities and consequently reduces their quality of life. Custom-made foot orthoses (FOs) are a common method of medical treatment that positively influences biomechanical factors such as the kinematics of the lower extremity and reduces pain perception in patients. However, there is a gap in research regarding the influence of different FO treatments on knee pain.
View Article and Find Full Text PDFEnviron Epigenet
January 2025
Institute of Human Genetics, School of Medicine, Pontificia Universidad Javeriana, Bogotá 110231, Colombia.
Fine particulate matter (PM), an atmospheric pollutant that settles deep in the respiratory tract, is highly harmful to human health. Despite its well-known impact on lung function and its ability to exacerbate asthma, the molecular basis of this effect is not fully understood. This integrated transcriptomic and epigenomic data analysis from publicly available datasets aimed to determine the impact of PM exposure and its association with asthma in human airway epithelial cells.
View Article and Find Full Text PDFMed Care Res Rev
January 2025
Department of Health Policy, Vanderbilt University School of Medicine, Nashville, TN, USA.
Post-acute care users in Medicare Advantage (MA) plans may seek coverage changes if facing issues with plan benefits. In 2019, the Centers for Medicare and Medicaid Services extended the deadline to disenroll from an MA plan from February 14 to March 31 and, for the first time, permitted beneficiaries to switch to a different MA plan instead of traditional Medicare. Using 2016-2019 Medicare administrative data, we implemented a difference-in-differences approach to evaluate the impact of this policy on disenrollment from a plan within 1 month of initiating skilled nursing facility or home health services.
View Article and Find Full Text PDFJ Neurol Neurosurg Psychiatry
January 2025
Multiple Sclerosis International Federation, London, UK.
Background: Limited data are available on the global rates of paediatric multiple sclerosis. Here, we report on the estimated worldwide prevalence of paediatric MS.
Methods: We included paediatric prevalence data in 2020-2022 (Multiple Sclerosis International Federation Atlas of MS) and the prevalence of child neurologists (International Child Neurology Association).
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