AI Article Synopsis
- Asymmetric total synthesis of danicalipin A was successfully completed, focusing on a specific method for adding chlorine atoms.
- Researchers assessed the biological effects of synthetic danicalipin A, its enantiomer (mirror image), and their racemic mixture on brine shrimp.
- The study found that both enantiomers exhibited nearly identical biological activity.
Article Abstract
Asymmetric total synthesis of danicalipin A was achieved. The synthesis was characterized by diastereoselective introduction of chlorine atoms. Biological activities with synthetic danicalipin A, its enantiomer, and racemate were also evaluated toward brine shrimp. Both enantiomers of danicalipin A showed almost the same activity.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1021/ol102882a | DOI Listing |
Publication Analysis
Top Keywords
asymmetric total
8
total synthesis
8
synthesis danicalipin
8
danicalipin
4
danicalipin evaluation
4
evaluation biological
4
biological activity
4
activity asymmetric
4
danicalipin achieved
4
achieved synthesis
4
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!