Objective: To determine the number of rattlesnake bites in pregnant women reported to U.S. poison centers and evaluate whether differences in management, treatments, or outcomes exist between pregnant and non-pregnant female bite victims.
Study Design: Review was conducted of the database of the American Association of Poison Control Centers (AAPCC). Exposures coded as rattlesnake bites between 2001 and 2007 were included for all reproductive-age women (15-45 years).
Results: Sixty-one poison control centers reported a total of 8,413 rattlesnake bites, with 767 (9.1%) involving reproductive-age women. Of these, 11 (1.4%) were pregnant. There were no significant differences between pregnant and nonpregnant victims with regard to rates of hospital admission, antivenom administration, or overall outcome codes. There were no adverse reactions to antivenom in pregnant women and no maternal deaths or fetal losses while in the hospital or during the period of poison center follow-up.
Conclusion: This rare condition is associated with favorable short-term pregnancy outcomes in the AAPCC database. In the absence of definitive evidence, we recommend standard management, including antivenom when indicated and extended fetal monitoring.
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Toxins (Basel)
December 2024
Poison Control Center, The University of Arizona College of Pharmacy, Tucson, AZ 85724, USA.
The onset, progression, and severity of pain following rattlesnake envenomation are highly variable between patients. Pain can be severe and persistent, seemingly refractory to opioid analgesics. The ability of antivenom to directly relieve pain has not been well studied.
View Article and Find Full Text PDFInt J Mol Sci
November 2024
College of Veterinary Medicine, Gyeongsang National University, Jinju 52828, Republic of Korea.
Snakebite envenoming is a significant health threat, particularly in tropical regions, causing substantial morbidity and mortality. Traditional treatments, including antivenom therapy, have limitations and associated risks. This research aims to discover novel phytochemical antidotes for snakebites, specifically targeting the western diamondback rattlesnake () venom metalloproteinase Atrolysin.
View Article and Find Full Text PDFToxicon
January 2025
Teaching and Research Center, Francisca Mendes Heart Hospital Foundation, Manaus, 69097-720, Brazil; Research management, Hospital Foundation of Hematology and Hemotherapy of Amazonas, 69050-001, Brazil. Electronic address:
We evaluated the efficacy of freeze-dried Bothrops-Lachesis-Crotalus antivenom and liquid Crotalus antivenoms to neutralize Crotalus durissus ruruima (Cdr) venom (Roraima, Brazil) comparing with C. d. terrificus (Cdt) venom.
View Article and Find Full Text PDFCutis
October 2024
Department of Orthopaedic Surgery, University of Illinois Chicago.
Clin Toxicol (Phila)
January 2025
Department of Emergency Medicine, University of Alabama at Birmingham, Birmingham, AL, USA.
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