5-Hydroxytryptamine(2A) (5-HT(2A)) serotonin receptors are important pharmacological targets for a large number of central nervous system and peripheral serotonergic medications. In this review article I summarize work mainly from my lab regarding serotonin receptor anatomy, pharmacology, signaling and regulation. I highlight the role of serotonin receptor interacting proteins and the emerging paradigm of G-protein coupled receptor functional selectivity.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3110590 | PMC |
http://dx.doi.org/10.1016/j.neuropharm.2011.01.012 | DOI Listing |
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