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| http://dx.doi.org/10.1258/shorts.2010.010075 | DOI Listing |
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Metastatic melanoma: an unexpected cause of acute liver failure.
Clin J Gastroenterol
December 2024
Faculty of Medicine, Vincent's Clinical School, University of New South Wales, Sydney, Australia.
Acute liver failure secondary to metastatic melanoma is exceedingly rare with the literature limited to case reports. The disease itself presents with vague symptoms making diagnosis difficult without a high clinical suspicion. Further to this, the prognosis of acute liver failure secondary to metastatic melanoma is dismal.
View Article and Find Full Text PDFStercoral Colitis: An Unexpected Presentation in a Young Adolescent.
Cureus
March 2024
Emergency Medicine, Wayne State University Detroit Medical Center, Detroit, USA.
Stercoral colitis is an uncommon inflammatory condition primarily affecting individuals with chronic constipation, immobilization, and advanced age, occasionally manifesting in pediatric patients. It arises from the accumulation of impacted fecal matter, leading to colonic distension and subsequent fecaloma formation, culminating in pressure necrosis and perforation. Mortality rates can exceed 60% in vulnerable populations due to complications such as colonic perforation and ischemia.
View Article and Find Full Text PDFPractices surrounding antimicrobial use in patients managed with extracorporeal membrane oxygenation: An international survey.
J Crit Care
June 2024
Department of Pharmacy, NewYork-Presbyterian Hospital, New York, NY, United States of America; Center for Acute Respiratory Failure, Columbia University College of Physicians and Surgeons and NewYork-Presbyterian Hospital, New York, NY, United States of America. Electronic address:
Purpose: This study aimed to survey critical care clinicians and characterize their perception of antimicrobial dosing strategies in patients receiving extracorporeal membrane oxygenation (ECMO).
Methods: International, cross-sectional survey distributed to members of the Society of Critical Care Medicine in October 2022.
Results: Respondents were primarily physicians (45%), with 92% practicing in North America.
Causes of death among non-urgent patients in the emergency department who die within 30 days.
Dan Med J
September 2023
Department of Emergency Medicine, Copenhagen University Hospital - Herlev and Gentofte Hospital.
Introduction: Patients triaged as non-urgent in the emergency department constitute a diverse group with a low mortality rate assumed to be able to wait three hours for a physician. Little is known about the causes of death of non-urgent patients who die shortly after admission. We examined whether deaths among non-urgent patients were preventable.
View Article and Find Full Text PDFA Novel RUNX1 Genetic Variant Identified in a Young Male with Severe Osteoporosis.
JBMR Plus
September 2023
Department of Endocrinology Monash Health Melbourne Victoria Australia.
This case describes a young man with an unusual cause of severe osteoporosis and markedly deranged bone microarchitecture resulting in multiple fractures. A potentially pathogenic germline variant in the runt-related transcription factor 1 (RUNX1) gene was discovered by a focused 51-gene myeloid malignancy panel during investigation for his unexplained normochromic normocytic anemia. Further bone-specific genetic testing and a pedigree analysis were declined by the patient.
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