A new class of anti-biofilm compounds possessing 1,4-disubstituted-(1H)-1,2,3-triazolic cores was designed. Their efficient synthesis was performed by means of click chemistry through 1,3-dipolar cycloadditions. Two compounds were found to act as specific anti-biofilm agents against a gram negative species.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.bmcl.2010.12.134 | DOI Listing |
Publication Analysis
Top Keywords
anti-biofilm compounds
8
targeting bacterial
4
bacterial biofilms
4
biofilms design
4
design terpenoid-like
4
terpenoid-like library
4
library non-toxic
4
non-toxic anti-biofilm
4
compounds class
4
class anti-biofilm
4
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!