AI Article Synopsis
- Prediabetes is characterized by impaired fasting glucose (IFG) and impaired glucose tolerance (IGT), which significantly increase the risk of developing diabetes and cardiovascular diseases compared to individuals with normal glucose levels.
- Evidence suggests that even glucose levels lower than the current prediabetes criteria can pose similar health risks, especially in high-risk populations.
- There's a need for research to broaden the understanding of prediabetes beyond strict definitions to better assess and address the risks associated with this condition.
Article Abstract
Diabetes evolves through prediabetes, defined as impaired fasting glucose (IFG) and/or impaired glucose tolerance (IGT). Subjects with IFG/IGT have an increased risk of developing diabetes and a higher prevalence of cardiovascular disease than normoglycemic individuals. However, there is considerable evidence that glucose levels lower than those meeting the current definition of prediabetes may also be associated with similar concerns, particularly in high-risk individuals in accordance with a continuous glycemic risk perspective. Therefore, an absolute definition of prediabetes may underestimate the implications and vastness of this disorder. Research should focus on these aspects to minimize the risk of developing a preventable condition.
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| http://dx.doi.org/10.1016/j.mcna.2010.11.002 | DOI Listing |
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