An amino oxide and three quaternary ammonium salts were investigated for antimicrobial activity. All compounds had low MIC against gram positive bacteria. Despite high MIC the ammonium salts gave good killing of Pseudomonas aeruginosa in time kill experiments. These quaternary ammonium salts may be useful for disinfection as they are easily broken down in the environment.
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Eur J Med Chem
December 2024
Departamento de Química Orgánica, Universidad Autónoma de Madrid, Cantoblanco, 28049, Madrid, Spain; Institute for Advanced Research in Chemical Sciences (IAdChem), Universidad Autónoma de Madrid, Cantoblanco, 28049, Madrid, Spain. Electronic address:
Four photosensitizers PS1a-PS4a consisting in multicationic ruthenium(II) phthalocyanines (RuPcs) have been evaluated in photodynamic inactivation (PDI) of multiresistant microorganisms. The RuPcs, bearing from 4 to 12 terminal ammonium salts, have been designed to target the microorganisms cytoplasmic cell membrane and display high singlet oxygen quantum yields. In addition, PS3a and PS4a were conceived to exhibit multi-target localization by endowing them with amphiphilic character, using two different structural approaches.
View Article and Find Full Text PDFACS Appl Mater Interfaces
January 2025
Institute of New Energy Technology, College of Physics & Optoelectronic Engineering, Jinan University, Guangzhou 510632, China.
The addition of organic cationic iodides to form low-dimensional perovskite is an essential strategy for defect passivation in perovskite solar cells (PSCs). Specially, the 2D/3D perovskite structure can combine the stability of 2D perovskite and the high charge transport performance of 3D perovskite. Here, we introduced phenylammonium hydroiodide salts with different alkyl chain lengths into PSCs precursor solution to research the influence on formation of perovskite thin films and the photovoltaic performance of PSCs.
View Article and Find Full Text PDFPolymers (Basel)
December 2024
School of Materials Science and Engineering, Nanjing Institute of Technology, Nanjing 211167, China.
In this study, CO reacted with a curing agent through nucleophilic addition to form ammonium salts, enabling the stable capture and internal release of CO, which achieved gas-phase nucleation and foaming. Additionally, the introduction of wave-absorbing agents improved the absorption mechanism and promoted uniform foaming. This nucleation-free foaming process relies on the induced growth of gas nuclei and the synergistic effect of the wave-absorbing agents, effectively preventing the uneven foaming issues caused by traditional nucleating agents.
View Article and Find Full Text PDFInt J Dent Hyg
January 2025
Department of Stomatology, Clinic of Stomatology, Shantou University Medical College, Shantou, China.
Objective: The aim of this systematic review is to explore the effectiveness of different methods of reducing contamination and biofilms in dental unit waterlines (DUWLs) and to provide reference for future standardisation of disinfection practices in dental clinic.
Methods: This systematic review searched PubMed and Web of Science databases for DUWL disinfection studies from 2013 to 2023, following Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines and Synthesis Without Meta-analysis, additional extracting relevant data based on predefined inclusion and exclusion criteria.
Results: The study review identified 8442 articles, with 58 included after rigorous screening.
Anal Chem
January 2025
State Key Laboratory of Southwestern Chinese Medicine Resources, School of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, China.
Quaternary ammonium salts (QAs) are a class of highly active compounds widely used in medicine and agriculture. However, many QAs lack a conjugated system, making their recognition and quantitation challenging. Stachydrine is a representative unconjugated QA with a high content in Houtt.
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