Irradiation stability of folic Acid in powder and aqueous solution.

J Agric Food Chem

Instituto de Pesquisas Energéticas e Nucleares (IPEN-CNEN/SP) , Centro de Tecnologia das Radiações, Av. Prof. Lineu Prestes, 2242, 05508-910, São Paulo, Brazil.

Published: February 2011

This study attempts to examine the folic acid stability after irradiation treatment, under different physical states, pH values, and atmosphere conditions. Aqueous folic acid samples, folic acid in powder, and wheat flour fortified with folic acid were irradiated by an electron beam (E-beam) between 0 (control) and 10.0 kGy. It was realized that the physical state of folic acid plays an important role on its stability toward E-beam processing, being largely unstable in solution, no matter the pH and atmosphere conditions assayed. Otherwise, folic acid in powder showed huge irradiation stability, even when mixed in a dry food matrix, such as fortified wheat flour samples.

Download full-text PDF

Source
http://dx.doi.org/10.1021/jf103977qDOI Listing

Publication Analysis

Top Keywords

folic acid
28
acid powder
12
irradiation stability
8
atmosphere conditions
8
wheat flour
8
folic
7
acid
7
stability folic
4
powder aqueous
4
aqueous solution
4

Similar Publications

Advanced-stage duodenal cancer in pregnancy.

BMJ Case Rep

January 2025

Maternal Fetal Medicine, University of Louisville Hospital, Louisville, Kentucky, USA.

This is a case report of a pregnant patient diagnosed with advanced-stage duodenal cancer in the second trimester. To the author's knowledge, there are no studies that describe the management of advanced duodenal cancer during pregnancy and this case highlights the importance of creating a multidisciplinary team and incorporating shared decision-making when discussing diagnostic workup and treatment options, including the use of cytotoxic therapy during pregnancy, with patients. This study will also discuss maternal and fetal outcomes after the administration of FOLFOX (leucovorin, fluorouracil and oxaliplatin) chemotherapy during the second trimester.

View Article and Find Full Text PDF

Evaluating the anticancer effects of carnosic acid against breast cancer: An In Vitro investigation.

Tissue Cell

January 2025

Department of Biophysics, Faculty of Advanced Technologies, University of Mohaghegh Ardabili, Namin, Iran. Electronic address:

Background: Carnosic acid (CA) has potential anti-cancer properties, but its effectiveness can be improved by combining it with Folic acid (FA). This research aimed to evaluate the impact of CA and CA-FA conjugate on breast cancer cell lines (MCF-7, MDA-MB-231, and MCA10).

Materials And Methods: The viability of the cell lines was measured using the MTT assay, and the IC₅₀ was determined to compare the cytotoxicity of CA and CA-FA.

View Article and Find Full Text PDF

Dementia Care Research and Psychosocial Factors.

Alzheimers Dement

December 2024

University of Georgia, College of Pharmacy, Athens, GA, USA.

Background: Lipids are key modulators in the pathogenesis of Alzheimer's disease (AD). Dysregulation of lipid homeostasis may disrupt the blood brain barrier, alter myelination, disturb cellular signaling and cause abnormal processing of the amyloid precursor protein. The purpose of this scoping review was to evaluate fatty acid supplementation in patients with AD.

View Article and Find Full Text PDF

A multitude of studies have presented inconsistent outcomes regarding the association between maternal folic acid (FA) and/or multivitamin (MV) supplementation and congenital heart disease (CHD) in offspring. This study aimed to estimate supplementation time and CHD based on a prospective China birth cohort study (CBCS). In the CBCS, 114,670 singleton pregnant women who had pregnancy outcomes until August 2021 and responded to the early pregnancy questionnaire were recruited.

View Article and Find Full Text PDF

Background: Orofacial cleft is among the most common craniofacial malformations. It presents a complex and multifactorial etiology that involves genetic and environmental factors. One of the etiological factors is consanguinity (marriage between blood relatives).

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!