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Two-step generation of monodisperse agarose-solidified double emulsions (w/w/o) excluding an inner oil barrier.
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Fraunhofer Institute for Molecular Biology and Applied Ecology (IME), Branch for Bioresources, 35392 Giessen, Germany.
Miniaturization of biomedical and chemical research areas is performed using microfluidic techniques. Droplet-based microfluidic applications are of high interest for various applications, e.g.
View Article and Find Full Text PDFMonodisperse Alginate Microcapsules with Spatially Confined Bioactive Molecules via Microfluid-Generated W/W/O Emulsions.
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A simple process is developed for the one-step preparation of dual-compartment alginate microcapsules with controlled size and structure from microfluid-generated water-in-water-in-oil (W/W/O) emulsion droplet. Unlike other methods that rely on transient W/W/O emulsion droplet, we introduce an aqueous two-phase system (ATPS) to form a stable W/W/O emulsion droplet as a template for preparing dual-compartment alginate microcapsules. Two different bioactive molecules are able to be spatially confined encapsulated in the shell and core of alginate microcapsules due to the partitioning effect of ATPS and the high viscosity of alginate solution.
View Article and Find Full Text PDFMonodisperse water-in-water-in-oil emulsion droplets.
Chemphyschem
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Department of Material and Energy Science, Graduate School of Environmental Science, Okayama University, 3-1-1 Tsushima-Naka, Kita-ku, Okayama 700-8530, Japan.
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