Background: Dimeticone 4% lotion is an effective and widely accepted treatment for head louse infestation. However, it is a highly mobile fluid that some people find difficult to apply and is mainly left on the hair for 8 hours or overnight. User preference is for a more manageable and viscous product that can be used with a short application time.
Findings: This proof of concept study in 41 people investigated dimeticone 4% liquid gel, a product that is easier to apply than the lotion, applied for 15 minutes on two occasions a week apart. We found that head lice were eliminated from all participants following the first application of product. We did not find lice of any stage on any participant during four post treatment assessments and particularly, unlike other treatments, no young nymphs on days 1 and 6 prior to the second treatment, indicating ovicidal as well as pediculicidal activity.
Conclusions: Dimeticone 4% liquid gel has demonstrated efficacy greater than other similar products and the evidence obtained indicates elimination of head louse infestation with a single 15 minute application.
Trial Registration: Current Controlled Trials ISRCTN59227204.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3038924 | PMC |
| http://dx.doi.org/10.1186/1756-0500-4-15 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Comparative efficacy of chemical and botanical pediculicides in Thailand and 4% dimeticone against head louse, Pediculus humanus capitis.
PLoS One
June 2023
Department of Parasitology, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand.
Head louse infestations remain a global public-health concern due to increased resistance of lice to artificial pediculicides. In Thailand, there is a lack of comparative data on the current efficacy of pediculicides for treating head lice. In this study, we explored the status of botanical and toxic synthetic pediculicides with that of 4% dimeticone liquid gel for treating head lice in Thailand.
View Article and Find Full Text PDFNeutron Reflectometry & Simultaneous Measurements of Rheology and Small Angle Neutron Scattering Studies for Polyether Modified Silicone Vesicle Systems.
J Oleo Sci
October 2022
Comprehensive Research Organization for Science and Society (CROSS).
Polyethyleneglycol 12 mol / polydimethylsiloxane co-polymer (PEG-12 dimethicone) is a type of polyether modified silicone (PEMS), which can form a lamellar liquid crystalline phase, and is widely used in cosmetics. The structural changes of PEG-12 dimethicone caused by water contents as well as shear flow were evaluated using simultaneous measurements of rheology and small angle neutron scattering (Rheo-SANS) and neutron reflectometry (NR). At high PEG-12 dimethicone concentrations (≥ 36 wt%), a reorientation of plate-like lamellar structures were observed and the neutral orientation was the most favorable.
View Article and Find Full Text PDFFactors to control the alignment of surface-treated titanium dioxide powders to maximize performance of sunscreens.
Int J Cosmet Sci
February 2023
Department of Applied Chemistry, Faculty of Science and Technology, Keio University, Yokohama, Japan.
Objective: Titanium dioxide powders are contained in a large class of colour cosmetics and sunscreen formulas. When they are used, the formation of a uniform functional powder layer on the skin is an important factor to show their functionality, such as aesthetic and UV protection. Attempts were made to extract the factors that affect the UV shielding ability of the deposited powder layer.
View Article and Find Full Text PDFThermal Catalytic-Cracking Low-Density Polyethylene Waste by Metakaolin-Based Geopolymer NaA Microsphere.
Molecules
April 2022
Guangxi Key Lab of Petrochemical Resource Processing and Process Intensification Technology, School of Chemistry and Chemical Engineering, Guangxi University, Nanning 530004, China.
Metakaolin-based geopolymer microspheres (MGM) with hierarchical pore structures were prepared by suspension dispersion method in dimethicone at 80 °C. The hydrothermal modification of MGM was carried out at a lower temperature of 80 °C, and a NaA molecular sieve converted from metakaolin-based geopolymer (NMGM) with good crystal structure was prepared and applied in thermal catalytic cracking of low-density polyethylene (LDPE) reaction. The one-pot two-stage thermal catalytic cracking of LDPE was carried out in a 100 mL micro-autoclave under normal pressure.
View Article and Find Full Text PDFApplication of factorial experimental design for optimization and development of color lipstick containing antioxidant-rich Sacha inchi oil.
Pak J Pharm Sci
July 2021
Department of Pharmaceutical Sciences, Faculty of Pharmacy, Chiang Mai University, Chiang Mai, Thailand/Innovation Center for Holistic Health, Nutraceuticals and Cosmeceuticals, Faculty of Pharmacy, Chiang Mai University, Chiang Mai, Thailand.
This study aimed to optimize and develop the color lipstick formulation containing antioxidant-rich Thai Sacha inchi oil using full factorial experimental design. Antioxidant capacity of Sacha inchi oil was elucidated using DPPH and linoleic acid peroxidation assays. The y-tocopherol content of the oil was also determined by high-performance liquid chromatography.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!