[The pathogenesis of primary immune thrombocytopenia].

Ugeskr Laeger

Afsnit 7521, Institut for Inflammationsforskning, Finsenscenter, Rigshospitalet, 2200 København N, Denmark.

Published: January 2011

Primary immune thrombocytopenia (ITP)--formerly known as idiopathic thrombocytopenic purpura--is an autoimmune disorder characterized by immune-mediated thrombocytopenia. The aetiology of ITP remains unknown, but studies have shown that multiple immunological mechanisms are involved in the pathogenesis of ITP.This article aims to provide an overview of our knowledge of the pathogenesis of ITP.

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