Background: Coronary angiography is the current standard method to evaluate coronary atherosclerosis in patients with suspected angina pectoris, but non-invasive CT scanning of the coronaries are increasingly used for the same purpose. Low-density lipoprotein (LDL) cholesterol and other lipid and lipoprotein variables are major risk factors for coronary artery disease. Small dense LDL particles may be of particular importance, but clinical studies evaluating their predictive value for coronary atherosclerosis are few.
Methods: We performed a study of 194 consecutive patients with chest pain, a priori considered of low to intermediate risk for significant coronary stenosis (>50% lumen obstruction) who were referred for elective coronary angiography. Plasma lipids and lipoproteins were measured including the subtype pattern of LDL particles, and all patients were examined by coronary CT scanning before coronary angiography.
Results: The proportion of small dense LDL was a strong univariate predictor of significant coronary artery stenosis evaluated by both methods. After adjustment for age, gender, smoking, and waist circumference only results obtained by traditional coronary angiography remained statistically significant.
Conclusion: Small dense LDL particles may add to risk stratification of patients with suspected angina pectoris.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3038964 | PMC |
| http://dx.doi.org/10.1186/1476-511X-10-21 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Low-Impedance Hybrid Carbon Structures on SiO: A Sequential Gas-Phase Coating Approach.
Small Methods
January 2025
BCMaterials, Basque Centre for Materials, Applications and Nanostructures; UPV/EHU Science Park, Leioa, 48940, Spain.
Carbon coating on SiO surface is crucial for enhancing initial Coulombic efficiency (ICE) and cycling performance in batteries, while also buffering volume expansion. Despite its market prevalence, the effects of the carbon layer's quality and structure on the electrochemical properties of SiO remain underexplored. This study compares carbon layers produced via gas-phase and solid-phase coating methods, introducing an innovative technique that sequentially uses two gases to develop a low-impedance hybrid carbon structure.
View Article and Find Full Text PDFExploring freshwater soundscapes of tropical marshland habitats in Southeast Asia: insights into auditory sensory adaptation of wild Siamese fighting fish .
PeerJ
January 2025
Institute of Science and Environment, University of Saint Joseph, Macao, Macao S.A.R., China.
While soundscapes shape the structure and function of auditory systems over evolutionary timescales, there is limited information regarding the adaptation of wild fish populations to their natural acoustic environments. This is particularly relevant for freshwater ecosystems, which are extremely diverse and face escalating pressures from human activities and associated noise pollution. The Siamese fighting fish is one of the most important cultured species in the global ornamental fish market and is increasingly recognized as a model organism for genetics and behavioural studies.
View Article and Find Full Text PDFPre-Lithiated Silicon-Based Composite Anode for High-Performance All-Solid-State Batteries.
Small
January 2025
College of Energy, Xiamen University, Xiamen, Fujian, 361102, China.
Silicon is widely recognized as a promising anode material for all-solid-state batteries (ASSBs) due to exceptional specific capacity, abundant availability, and environmental sustainability. However, the considerable volume expansion and particle fragmentation of Si during cycling lead to significant performance degradation, limiting its practical application. Herein, the development of a pre-lithiated Si-based composite anode (c-LiSi) is presented, designed to address the key challenges faced by Si-based anodes, namely severe volume changes and low electrochemical stability.
View Article and Find Full Text PDFEffects of a Habitat Integrity Gradient on the Diversity of Odonates in the Legal Amazonia Zone of the Brazilian State of Maranhão.
Neotrop Entomol
January 2025
Lab of Environmental Sciences and Biodiversity, Univ Estadual do Maranhão, São Luís, Maranhão, Brazil.
The diverse ecosystems of the Amazon biome play a vital role in the maintenance of biodiversity and delivering essential ecosystem services at both local and global levels. Small-bodied generalist insects, such as those from the order Odonata, contribute significantly to these services and are recognized as sensitive bioindicators of environmental quality. The present study evaluated the diversity and distribution of adult odonates in the Legal Amazonia zone of the Brazilian state of Maranhão, to identify the key environmental drivers shaping local odonate communities.
View Article and Find Full Text PDFNon-Stoichiometric Amorphous Calcium Carbonate Forms in Macromolecular Condensates via Interphase Diffusion.
Small
January 2025
Dept. of Plant and Environmental Sciences, Weizmann Institute of Science, Rehovot, 7610001, Israel.
Transient amorphous phases are known as functional precursors in the formation of crystalline materials, both in vivo and in vitro. A common route to regulate amorphous calcium carbonate (ACC) crystallization is via direct interactions with negatively charged macromolecules. However, a less explored phenomenon that can influence such systems is the electrostatically driven formation of Ca-macromolecule dense phases.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!