AI Article Synopsis
- The main treatment for repeated cardiac allograft rejection that doesn't respond to standard immunotherapy is retransplantation.
- If retransplantation isn't an option, other strategies need to be explored for managing the condition.
- This report details a case where a 35-year-old man who had two heart transplants successfully managed ongoing rejection with five consecutive 14-day treatments of OKT3.
Article Abstract
The treatment for recurrent cardiac allograft rejection refractory to conventional immunotherapy is retransplantation. When retransplantation is not possible, alternative approaches must be undertaken. This report reviews the successful management of persistently recurring rejection using five serial 14-day courses of OKT3 in a 35-year-old man after two heart transplantations.
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