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Reprogramming the future: Capitalizing on embryo culture by advancing stem cell technologies in the fight against rare genetic disorders.
Intractable Rare Dis Res
May 2024
Laboratory for Reproductive Immunology, Obstetrics and Gynecology Hospital of Fudan University, Shanghai, China.
Capitalizing on breakthroughs in reproductive genetics, the utilization of embryo culture and stem cell technologies heralds a transformative era in addressing global challenges posed by rare genetic diseases. These cutting-edge practices illuminate the intricacies of early human development, elucidate the mechanisms behind rare diseases, and guide the development of potential therapies. Balancing this remarkable innovation with necessary ethical considerations, these technologies have the potential to revolutionize the trajectory of rare genetic disorders, transforming the landscape of diagnosis, treatment, and genetic counseling while offering renewed hope for affected individuals and families worldwide.
View Article and Find Full Text PDFRejuvenation: From the Fictional Dr Heidegger (1837) to Pioneering Modern Plastic Surgeons (1901-1912).
J Craniofac Surg
July 2024
Department of Plastic Surgery, Daejeon Eulji Medical Center, Eulji University, Daejeon.
This study aims to identify criticisms of rejuvenation and cosmetic surgery through an analysis of "Dr Heidegger's Experiment" (1837), written by Nathaniel Hawthorne. Dr Heidegger an eccentric, aged scientist, invites 4 elderly friends to be his subjects of study. The guests drink the water from the "fountain of Youth.
View Article and Find Full Text PDFGenetically predicted causal associations between periodontitis and psychiatric disorders.
BMJ Ment Health
November 2023
Department of Gastroenterology, Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou, Guangdong, China
Background: Psychiatric disorders have serious harm to individuals' lives with high disease burden. Observational studies reported inconsistent associations between periodontitis and some psychiatric disorders, and the causal correlations between them remain unknown.
Objective: This study aims to explore the causal associations between periodontitis and psychiatric disorders.
"Not by a Decree of Fate:" Ellen Richards, Euthenics, and the Environment in the Progressive Era.
J Hist Biol
October 2023
History Department, John Jay College of the City University of New York, 524 W. 59th St., New York, 10019, USA.
In 1904, Ellen Richards introduced "euthenics." By 1912, Lewellys Barker, director of medicine and physician-in-chief at Johns Hopkins Hospital, would tell the New York Times that the "task of eugenics" and the "task of euthenics" was the "Task for the Nation." Alongside the emergence of hereditarian eugenics, where fate was firmly rooted in heredity, this article places euthenics into the same Progressive Era demands for the scientific management over environmental issues like life and labor, health and hygiene, sewage and sanitation.
View Article and Find Full Text PDFComment about the safety of excipients used to dissolve topiramate for parenteral administration.
Epilepsy Behav
August 2023
Department of Neurology, Christian Doppler University Hospital, Paracelsus Medical University, Salzburg, Austria; Center for Cognitive Neuroscience, Salzburg, Austria.
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