Severe disseminated is rare while localized, contained disease is common. We report a family with disseminated coccidioidomycosis due to a novel homozygous C186Y mutation in interleukin (IL)-12 receptor β1. This family confirms the centrality of the IL-12/IFN-γ axis to human immunity to spp.
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|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3060907 | PMC |
| http://dx.doi.org/10.1093/cid/ciq215 | DOI Listing |
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