The results of treatment of 245 patients with purulent diseases of the soft tissues are discussed. The course of the wound process was most favourable with the use of immobilized trypsin on gauze in the management of wounds formed after surgical debridement of purulent foci by means of CO2 laser. The method made it possible to accelerate the processes of necrolysis, provide a stable low level of dissemination of bacteria in the wound tissues, reduce the term of preparation of the wound for the application of secondary sutures and the terms of healing.
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