Shrinking lung syndrome in pregnancy complicated by antiphospholipid antibody syndrome.

Obstet Gynecol

From the Division of Maternal Fetal Medicine and the Mayo Medical School, Mayo Clinic College of Medicine, Rochester, Minnesota.

Published: February 2011

Background: Shrinking lung syndrome is characterized by pulmonary compromise secondary to unilateral or bilateral paralysis of the diaphragm.

Case: Shrinking lung syndrome was diagnosed in a patient with antiphospholipid syndrome after a cesarean delivery at 28 4/7 weeks of gestation. Signs and symptoms included unexplained right-side chest pain, dyspnea, tachypnea, and absent breath sounds at the right base of the lungs. After initiation of corticosteroids, her symptoms resolved.

Conclusion: Although seen in association with systemic lupus erythematosus, shrinking lung syndrome has not been described with antiphospholipid syndrome or during pregnancy. Diagnosis and awareness are important because treatment with moderate- to high-dose corticosteroids appears to improve the clinical outcome.

Download full-text PDF

Source
http://dx.doi.org/10.1097/AOG.0b013e318206c254DOI Listing

Publication Analysis

Top Keywords

shrinking lung
16
lung syndrome
16
syndrome pregnancy
8
antiphospholipid syndrome
8
syndrome
7
shrinking
4
pregnancy complicated
4
complicated antiphospholipid
4
antiphospholipid antibody
4
antibody syndrome
4

Similar Publications

[Savolitinib Induced Pathological Complete Response in Non-small Cell Lung Cancer with MET Amplification: A Case Report].

Zhongguo Fei Ai Za Zhi

November 2024

Department of Pulmonary Oncology, Tianjin Medical University Cancer Institute & Hospital, National Clinical Research Center for Cancer, Tianjin's Clinical Research Center for Cancer, Tianjin 300000, China.

Mesenchymal-epithelial transition factor (MET) gene mutation is a large class of mutations commonly seen in non-small cell lung cancer (NSCLC). MET mutation includes subtypes such as MET exon 14 skipping mutation (METex14m) and MET amplification (METamp). For advanced NSCLC with METex14m, Savolitinib has a high sensitivity as a member of tyrosine kinase inhibitors (TKIs).

View Article and Find Full Text PDF

Background: Thymic cysts can be classified as congenital or acquired. Most thymic cysts do not change in size over a short period of time. Although very rare, thymic cyst rupture is associated with serious complications, such as mediastinal hemorrhage and hemothorax.

View Article and Find Full Text PDF

The patient was a 21-year-old man with a shadow on a chest roentgenogram taken during a medical checkup. According to blood testing, thoracoabdominal computed tomography, head magnetic resonance imaging, and lung tumor biopsy, we diagnosed a primary retroperitoneal germ cell tumor with multiple lung and brain metastases. Induction chemotherapy (4 courses of Bleomycin, Etoposide and Cisplatin) was started immediately.

View Article and Find Full Text PDF

Objectives: In patients with interstitial lung disease (ILD), the diaphragm typically rises as the lungs chronically shrink. However, the grade of restriction differs in each patient. It is currently unknown, how disparities between actual and predicted recipient total lung capacity (TLC), impact changes in lung function parameters and long-term outcomes following lung transplantation (LTx).

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!