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Calix[6]arene-Functionalized Photonic Hydrogel Biosensor for Naked-Eye Cholesterol Detection Based on Supramolecular Host-Guest Interactions.
ACS Sens
October 2024
College of Chemistry and Environment, Southwest Minzu University, Chengdu, Sichuan 610225, China.
Cholesterol (CHO) is an essential constituent of human cellular tissues and a crucial activity indicator for the clinical diagnosis and prevention of various diseases. Abnormal CHO levels can lead to various cardiovascular diseases, including coronary heart disease, cerebral thrombosis, and atherosclerosis. Thus, developing simple and effective methods for CHO detection is of great significance.
View Article and Find Full Text PDFActivated PARP1/FAK/COL5A1 signaling facilitates the tumorigenesis of cholesterol-resistant ovarian cancer cells through promoting EMT.
Cell Signal
December 2024
Department of Nutrition and Food Hygiene, School of Public Health, Medical College of Soochow University, Suzhou, China. Electronic address:
Cancer cells require plentiful cholesterol for membrane biogenesis and other functional needs due to fast proliferating, leading to the interaction of cholesterol or its metabolites with cancer-related pathways. However, the impact of long-lasting high cholesterol concentrations on tumorigenesis and its underlying mechanisms remains largely unexplored. To the best of our knowledge, this study is the first to establish a cholesterol-resistant ovarian cancer cells, whose intracellular total cholesterol level up to 6-8 mmol/L.
View Article and Find Full Text PDFFermentation impact: A comparative study on the functional and biological properties of Banana peel waste.
Heliyon
August 2024
Deprtment of Animal Nutrition, The University of Agriculture Peshawar, Pakistan.
Banana fruit is a highly consumed and widely cultivated world food crop that generates plenty of waste globally. In this work, the phytochemical, nutritional, scavenging and therapeutic potentials of banana peel (BP) extracts were compared before and after fermentation. Halophilic fungi (, spp.
View Article and Find Full Text PDFGroundnut and tree nuts: a comprehensive review on their lipid components, phytochemicals, and nutraceutical properties.
Crit Rev Food Sci Nutr
July 2024
Instituto Multidisciplinario de Biología Vegetal (IMBIV - CONICET). Facultad de Ciencias Exactas, Físicas y Naturales - Universidad Nacional de Córdoba (UNC), Córdoba, Argentina.
The health benefits of nut consumption have been extensively demonstrated in observational studies and intervention trials. Besides the high nutritional value, countless evidences show that incorporating nuts into the diet may contribute to health promotion and prevention of certain diseases. Such benefits have been mostly and certainly attributed not only to their richness in healthy lipids (plentiful in unsaturated fatty acids), but also to the presence of a vast array of phytochemicals, such as polar lipids, squalene, phytosterols, tocochromanols, and polyphenolic compounds.
View Article and Find Full Text PDFAstragalus Extract Mixture HT042 Alleviates Dexamethasone-Induced Bone Growth Retardation in Rat Metatarsal Bones.
Nutrients
July 2024
Department of Herbal Pharmacology, College of Korean Medicine, Kyung Hee University, 26 Kyungheedae-ro, Dongdaemun-gu, Seoul 02447, Republic of Korea.
The most widely used synthetic glucocorticoid, dexamethasone (DEX), causes stunted growth in children when used excessively or for long periods of time; however, there are still plenty of pediatric patients require long-term treatment with DEX. As an alternative, growth hormone is used in combination, but it has side effects, a high cost, and psychological factors, and it is not satisfactory in terms of effectiveness. It is necessary to develop a safe and affordable treatment that can replace it.
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