Objective: To determine the prevalence of Mycobacterium avium subspecies paratuberculosis (Mptb) shedding by unvaccinated wethers compared with vaccinated ewes.
Methods: Six self-replacing, ovine Johne's disease (OJD)-infected Merino flocks that had been vaccinating lambs with Gudair(TM) for at least 5 years, but had not vaccinated their last two drops of wethers were studied. Faecal samples were collected in pools of 50 from 350 vaccinated ewes (1-2 years old) and from 350 unvaccinated wethers of the same age and were cultured to determine the presence of viable Mptb.
Results: The estimated prevalence of shedding sheep among the unvaccinated wethers was 6-fold greater than among the vaccinated female siblings (0.21% vs 1.27%), with faecal pools collected from unvaccinated wethers being 19-fold more likely to be positive than those from the vaccinated ewes.
Conclusion: Leaving wethers unvaccinated is likely to considerably increase pasture contamination with Mptb and potentially jeopardise disease control.
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http://dx.doi.org/10.1111/j.1751-0813.2010.00651.x | DOI Listing |
Objective: To determine the prevalence of Mycobacterium avium subspecies paratuberculosis (Mptb) shedding by unvaccinated wethers compared with vaccinated ewes.
Methods: Six self-replacing, ovine Johne's disease (OJD)-infected Merino flocks that had been vaccinating lambs with Gudair(TM) for at least 5 years, but had not vaccinated their last two drops of wethers were studied. Faecal samples were collected in pools of 50 from 350 vaccinated ewes (1-2 years old) and from 350 unvaccinated wethers of the same age and were cultured to determine the presence of viable Mptb.
Aust Vet J
April 1988
Animal Health Division, Department of Agriculture, South Perth, Western Australia.
Two hundred Merino wether hoggets were used to examine the effect of Corynebacterium pseudotuberculosis infection (caseous lymphadenitis) on wool production and bodyweight. Sheep which were challenged with C. pseudotuberculosis (artificially infected) and not vaccinated against this disease produced 0.
View Article and Find Full Text PDFN Z Vet J
March 1982
Wallaceville Animal Research Centre, Research Division, Ministry of Agriculture and Fisheries, Private Bag, Upper Hutt.
Groups of 10-12 Romney and Merino wethers were challenged simultaneously with homologous experimental footrot infection after having received the second of 2 doses of Bacteroides nodosus (strain 198) vaccine 0, 4, 8, 12, 16 and 20 weeks previously. Inoculations were carried out 28 days apart and unvaccinated sheep of both breeds were challenged as controls. Most Romneys that had been vaccinated up to 16 weeks prior to challenge were resistant to footrot whereas 8 of 10 controls were susceptible.
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