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A Scoping Review of Electronic Health Records-Based Screening Algorithms for Familial Hypercholesterolemia.
JACC Adv
December 2024
Division of Blood Disorders and Public Health Genomics, National Center on Birth Defects and Developmental Disabilities, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
Background: Familial hypercholesterolemia (FH) is a common genetic disorder that is strongly associated with premature cardiovascular disease. Effective diagnosis and appropriate treatment of FH can reduce cardiovascular disease risk; however, FH is underdiagnosed. Electronic health record (EHR)-based FH screening tools have been previously described to enhance the detection of FH.
View Article and Find Full Text PDFAssessment of adverse events stratified by timing of leadless pacemaker implantation with cardiac implantable electronic devices extraction due to infection: A systematic review and meta-analysis.
J Arrhythm
February 2025
Department of Cardiology Nagoya University Graduate School of Medicine Nagoya Japan.
Background: Removal of cardiac implantable electronic devices (CIEDs) is strongly recommended for CIED-related infections, and leadless pacemakers (LPs) are increasingly used for reimplantation. However, the optimal timing and safety of LP implantation after CIED removal for infection remains unclear.This systematic review and meta-analysis aimed to assess complication rates (all-cause mortality and reinfection) when LP implantation was performed simultaneously with or after CIED removal.
View Article and Find Full Text PDFChildhood adversity, emergent psychopathology, and adolescent-to-parent violence: Process mining trajectories from police and health service administrative data.
Front Child Adolesc Psychiatry
April 2023
Faculty of Health, Southern Cross University, Coffs Harbour, NSW, Australia.
Aim: To discover developmental risk trajectories for emerging mental health problems among a sample of adolescent family violence offenders to inform service delivery focused on early preventative interventions with children and their families.
Design: A retrospective case-series design employing data linkage.
Setting: An Australian regional location.
Social and executive functioning in individuals with autism spectrum disorder without intellectual disability: The case-control study protocol of the CNeSA study.
Front Child Adolesc Psychiatry
April 2023
Section of Neuroscience & Clinical Pharmacology, Department of Biomedical Science, University of Cagliari, Cagliari, Italy.
Several studies suggest that children and adolescents with autism spectrum disorder (ASD) often present deficits in executive functions (EFs). The research on cold EF shows a high heterogeneity across different cohorts of patients as well as different study designs, while studies investigating hot EF and their relationship with different ASD phenotypes are still limited and related only to specific domains, although this concept could contribute to clarify the phenotypical variability by explaining the difficulties encountered by individuals with ASD in daily life, where stimuli are often emotionally charged. With the aim to identify specific neuropsychological profiles in children and adolescents with ASD without intellectual disability, we designed a study protocol comparing a clinical sample of individuals with ASD to aged-matched (10-17 years) typically developing controls (TDC) on a neuropsychological test battery investigating both "cold" and "hot" EF with the purpose of further investigating their relationships with ASD symptoms.
View Article and Find Full Text PDFQuantifying animal social behaviour with ecological field methods.
R Soc Open Sci
January 2025
School of Biological Sciences, University of Bristol, Bristol, UK.
Field studies of social behaviour are challenging due to the need to record or infer interactions between multiple individuals, often under suboptimal environmental conditions or with potential disturbance by observers. Due to the limited field techniques available, we present a novel method to quantify social behaviours in the field by comparing the counts of individuals caught in traps across multiple locations sampled simultaneously. The distribution of individuals between traps gives the extent of aggregation, and phenotypic data allow for inference of non-random assortment.
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