Two complementary formats for kinase inhibitor screening are presented in which peptide-modified gold nanoparticles are enzymatically phosphorylated and rapidly aggregate on a surface or in solution by action of phosphospecific antibodies. The simple and rapid colourimetric response of the assays makes them an attractive approach for drug-screening applications.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1039/c0cc04903d | DOI Listing |
Publication Analysis
Top Keywords
kinase inhibitor
8
inhibitor screening
8
peptide-modified gold
8
single-step kinase
4
screening peptide-modified
4
gold nanoparticle
4
nanoparticle platform
4
platform complementary
4
complementary formats
4
formats kinase
4
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!