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Cell damage produced by magnetic fluid hyperthermia on microglial BV2 cells.
Sci Rep
August 2017
Nanoscience Institute of Aragón, University of Zaragoza, Zaragoza, Spain.
We present evidence on the effects of exogenous heating by water bath (WB) and magnetic hyperthermia (MHT) on a glial micro-tumor phantom. To this, magnetic nanoparticles (MNPs) of 30-40 nm were designed to obtain particle sizes for maximum heating efficiency. The specific power absorption (SPA) values (f = 560 kHz, H = 23.
View Article and Find Full Text PDFGalectin-3 in preneoplastic lesions of glioma.
J Neurooncol
January 2013
Department of Tumor Pathology, Gifu University Graduate School of Medicine, Yanagido 1-1, Gifu City, Gifu 501-1194, Japan.
Gliomas are the most common primary brain tumors in adults and have a poor prognosis. Galectin-3 is a β-galactosidase-binding lectin which is important in pre-mRNA splicing, regulation of cell proliferation, cell adhesion and apoptosis. Although galectin-3 has been shown as a glioma related marker and expression of galectin-3 has been reported to correlate with WHO grade in human gliomas, expression of galectin-3 in early neoplastic lesions such as early neoplastic proliferation (ENP) and microtumor is still far from fully understood.
View Article and Find Full Text PDFVEGF immunopositivity related to malignancy degree, proliferative activity and angiogenesis in ENU-induced gliomas.
J Mol Neurosci
February 2008
Laboratory of Clinical and Experimental Neuroscience (LaNCE), Department of Neuroscience, University of the Basque Country, Leioa, Spain.
Growth of solid tumors is highly dependent on angiogenesis. During tumor development, neoplastic cells switch to an angiogenic phenotype, playing a significant role in the expression of the vascular endothelial growth factor (VEGF). Seventy-two brain gliomas were induced in Sprague Dawley rats by prenatal exposure to ethylnitrosourea (ENU).
View Article and Find Full Text PDF[A case of glial microtumor treated with brachytherapy using MRI guided stereotactic system].
No Shinkei Geka
October 1993
Department of Neurological Surgery, Okayama University Medical School.
A 34 year old male suffered from convulsion on his right side with loss of consciousness. Neither plain nor enhanced CT could clearly demonstrate a lesion. However, a Gd-DTPA enhanced T1 weighted image (T1WI) demonstrated an enhancing lesion (2 cm in diameter) in the left frontal lobe including the motor cortex.
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