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Observational study of venous leg ulcer treated with a native collagen-alginate dressing and the impact on wound-related quality of life.
Wound Manag Prev
December 2024
Northwell Health System, Department of Surgery, Comprehensive Wound Care Healing and Hyperbaric, Lake Success, NY.
Background: Venous leg ulcers (VLUs) are associated with various physical and social adverse effects for patients but also contribute to a significant socioeconomic burden.
Purpose: To examine the clinical performance and safety of a collagen-alginate dressing in combination with standard wound care in non-healing VLUs.
Methods: In an observational, explorative, single-center study, VLUs of 60 patients were covered with a collagen-alginate dressing.
Application of clinician support tools to improve wound healing outcomes and simplify treatment selection for effective exudate management.
Wounds
December 2024
Smith+Nephew, Watford, Hertfordshire, UK.
Background: Achievement of moisture balance can be a critical factor affecting time to closure of nonhealing wounds, and dry wounds can take much longer to heal than those with high exudate levels. Whether the goal of management is to donate moisture to the wound or control excessive fluid until the cause has been identified and addressed, choice of dressing and other wound management products can affect nursing resources, clinical outcomes, concordance, and quality of life for the patient.
Case Reports: The cases discussed illustrate differences in management approaches for dry and wet wounds and show how clinician support tools (eg, tissue type, infection/inflammation, moisture imbalance, epithelial edge advancement [TIME] clinical decision support tool) can facilitate treatment decisions.
Degree of sulfation of freeze-dried calcium alginate sulfate scaffolds dramatically influence healing rate of full-thickness diabetic wounds.
Int J Biol Macromol
December 2024
Department of Cell Engineering, Stem Cells and Developmental Biology, Cell Science Research Center, ACECR, Royan Institute, Tehran, Iran. Electronic address:
Diabetic foot ulcer (DFU) is a chronic and non-healing wound in all age categories with a high prevalence and mortality in the world. An ideal wound dressing for DFU should possess the ability of adsorbing high contents of exudate and actively promote wound healing. Here, we introduced the calcium alginate sulfate as a new biomaterial appropriate for use in wound dressing to promote the healing of full-thickness ulcers in a diabetic mouse model.
View Article and Find Full Text PDFManagement of Foot Ulcers and Chronic Wounds with Amniotic Membrane in Comorbid Patients: A Successful Experience.
Biomedicines
October 2024
Laboratorio de Regeneración, Oncología Molecular y TGF-ß IMIB-Arrixaca, Biomedical Research Institute of Murcia (IMIB-Arrixaca), El Palmar, 30120 Murcia, Spain.
Chronic wounds are defined as those with disturbances in normal healing. They involve symptoms like exudate, odor, pain or impaired mobility, severely impacting life quality. In the case of patients with additional comorbidities, these are known to aggravate the healing impairment.
View Article and Find Full Text PDFHarnessing the Interactions of Wound Exudate Cells with Dressings Biomaterials for the Control and Prognosis of Healing Pathways.
Pharmaceuticals (Basel)
August 2024
Centre for Regenerative Medicine and Devices, University of Brighton, Huxley Building Lewes Road, Brighton BN2 4GJ, UK.
Article Synopsis
- The study examines how different types of wound dressings affect healing by analyzing their interactions with cellular components in acute surgical wounds 24 hours post-surgery.
- It compares Atrauman, a primary dressing made of synthetic fibers, with Melolin, a secondary hydrocolloid dressing, to observe their effects on healing pathways.
- Findings suggest that Atrauman retains beneficial cells that promote healing, while Melolin may hinder this process by absorbing key healing cells, indicating that wound dressing composition can significantly impact recovery outcomes.
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