Introduction: Training health care professionals on preventive measures of ventilator-associated pneumonia (VAP) reduces the incidence of this serious adverse effect.
Objectives: To evaluate the effectiveness of the non-pharmacological, VAP preventive program by comparing the incidence of VAP in two periods: pre- and post- training of the nursing staff of the intensive care unit (ICU).
Material And Methods: A comparative, observational study on the incidence of VAP and related-risk factors. Two prevalence cutoffs were used: prior to training (from October 2007 to June 2008) and post-training (from October 2008 to April 2009). The statistical analysis was performed with the SPSS v.15 statistical program, t-test or Mann-Whitney test for continuous variables and Chi-square or Fisher test for qualitative variables.
Results: A total of 69 patients were included in the pre-training period and 71 in the post-training. Age and gender percentages were similar in both groups. There was a greater number of risk factor for VAP in the pre-training period that was statistically significant only in the case of diabetes (27.5% versus 8.4%; P=.004). There were no differences regarding the treatment administered to both groups or number of days in ICU or mechanical ventilation (MV) days. Decreased rate of 6.01 to 1.91 VAP/1.000 ventilator days in the post-training period.
Conclusions: Preventive measures reduced the incidence of VAP in two samples of patients comparable in terms of risk factors. Nursing education is directly related to the results in patient safety.
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http://dx.doi.org/10.1016/j.enfi.2010.09.003 | DOI Listing |
Front Pediatr
January 2025
Department of Clinical Pharmacy, School of Pharmacy, Shiraz University of Medical Sciences, Shiraz, Iran.
Introduction: One of the most prevalent healthcare-associated infections in the pediatric intensive care unit is ventilator-associated pneumonia (VAP). VAP not only results in prolonged hospital and intensive care unit (ICU) stays but also imposes higher costs on patients and the healthcare system. Therefore, it is essential to implement preventive measures.
View Article and Find Full Text PDFInfect Drug Resist
January 2025
Science & Technology Innovation Center, Guangyuan Central Hospital, Guangyuan, People's Republic of China.
Objective: To explore the application of short-peptide enteral nutrition formulation in mechanically ventilated pediatric patients with severe pneumonia and its impact on rehabilitation outcomes, providing practical clinical evidence for the nutritional support strategy in critically ill pneumonia children.
Methods: This study retrospectively analyzed the clinical data of 90 neonatal pneumonia patients undergoing mechanical ventilation from May 2022 to December 2023. The patients were divided into an experimental group receiving short peptide enteral nutrition formulation via nasogastric tube and a control group receiving whole-protein enteral nutrition formulation via nasogastric tube.
J Clin Med
January 2025
Department of Surgical Sciences, University of Turin, 10126 Turin, Italy.
: Bacterial superinfections are common complications during viral infections, but the impact of multidrug-resistant (MDR) pathogens in critically ill patients affected by coronavirus disease 2019 (COVID-19) is still debated. : This is an observational, monocentric, and prospective study designed to investigate the incidence, risk factors, and outcomes of MDR bacterial superinfections in COVID-19 patients admitted to the intensive care unit (ICU). : A high incidence of superinfections (66%, 159/241) was observed: ventilator-associated pneumonia (VAP) (65%, 104/159) and bloodstream infection (BSI, 32%, 51/159) were the most common.
View Article and Find Full Text PDFMedicina (Kaunas)
January 2025
Division of Pulmonary and Critical Care Medicine Mayo Clinic, Rochester, MN 55905, USA.
: Ventilator-associated pneumonia (VAP) poses a significant threat to the clinical outcomes and hospital stays of mechanically ventilated patients, particularly those recovering from cardiac arrest. Given the already elevated mortality rates in cardiac arrest cases, the addition of VAP further diminishes the chances of survival. Consequently, a paramount focus on VAP prevention becomes imperative.
View Article and Find Full Text PDFPediatr Infect Dis J
December 2024
Section of Infectious Diseases, Department of Pediatrics, University of Colorado School of Medicine and Children's Hospital Colorado, Aurora, Colorado.
Background: Bacterial lower respiratory tract infection, particularly ventilator-associated pneumonia (VAP), is a significant cause of morbidity and mortality in children who require mechanical ventilation (MV). Microbiologic diagnosis has relied on bacterial culture, but reverse transcriptase polymerase chain reaction (RT-PCR) with bacterial targets is now available for clinical use. We compared the diagnostic performance of tracheal aspirate (TA) multiplex RT-PCR to culture in children requiring MV with suspected lower respiratory tract infection.
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