A novel synthesis of (di)-benzazocinones via an endocyclic N-acyliminium ion cyclisation.

Org Biomol Chem

Department of Chemistry, University College London, 20 Gordon Street, London, UK WC1H 0AJ.

Published: March 2011

The triflic acid-mediated endocyclic N-acyliminium ion cyclisation provides a facile synthesis of (di)-benzazocinones. On reduction of the 10-phenyl derivative, an unusually non-polar tertiary alkylamine was obtained.

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Source
http://dx.doi.org/10.1039/c0ob00559bDOI Listing

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