Objectives: We conducted a randomized clinical trial to test an integrated behavioral intervention designed to enhance using HIV treatment as prevention by improving medication adherence, reducing risks for other sexually transmitted infections, and minimizing risk compensation beliefs.
Methods: Individuals living with HIV/AIDS (n = 436) participated in a randomized clinical trial testing an intensive behavioral intervention aimed at reducing HIV transmission risks compared with an attention control condition. We used unannounced pill counts to monitor antiretroviral therapy adherence and computerized interviews to measure risk behaviors.
Results: The integrated transmission risk reduction intervention demonstrated increased antiretroviral therapy adherence and less unprotected intercourse with nonseroconcordant partners at 3- and 6-month follow-ups as well as fewer new sexually transmitted infections diagnosed over the 9-month follow-up period (adjusted odds ratio = 3.0; P < .05; 95% confidence interval = 1.01, 9.04). The integrated intervention also reduced behavioral risk compensation beliefs.
Conclusions: A theory-based integrated behavioral intervention can improve HIV treatment adherence and reduce HIV transmission risks. HIV treatment as prevention should be bundled with behavioral interventions to maximize effectiveness.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3036694 | PMC |
| http://dx.doi.org/10.2105/AJPH.2010.197608 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Cognitive behavioral therapy for adolescents with eating disorders, with particular regard to clinical perfectionism.
Psychiatr Pol
October 2024
Katedra Psychologii Klinicznej i Psychoprofilaktyki, Instytut Psychologii, Uniwersytet Szczeciński.
Eating disorders are a considerable and prevalent problem among adolescents. Due to their significant adverse health consequences, it is of key importance to examine available treatment options and their effects. Despite the shared criteria for eating disorders in adolescents and adults, the diagnostic and therapeutic processes in the former require distinct specialist interventions, including the entire family environment.
View Article and Find Full Text PDFCognitive behavioral therapy for the treatment of separation anxiety disorder in children - a research review and case study.
Psychiatr Pol
October 2024
Poradnia Poza Schematami w Warszawie.
The aim of this paper is to review studies available in scientific databases on the effectiveness of cognitive behavioral therapy programmes for separation anxiety disorder in children. The paper also includes a presentation of a clinical description of therapy for a 12-year-old girl with a diagnosis of separation anxiety according to ICD-10. The most widely researched and sole protocol for working with children with anxiety disorders in Poland, the Coping Cat programme, was used as the basic protocol.
View Article and Find Full Text PDFInaudible airborne ultrasound affects emotional states in the olfactory bulbectomized rat depression model.
Sci Rep
January 2025
Laboratory of Pharmacology, Department of Pharmacy, Faculty of Pharmaceutical Sciences, Tokyo University of Science, Chiba, Japan.
Recently, exposure to sounds with ultrasound (US) components has been shown to modulate brain activity. However, the effects of US on emotional states remain poorly understood. We previously demonstrated that the olfactory bulbectomized (OBX) rat depression model is suitable for examining the effects of audible sounds on emotionality.
View Article and Find Full Text PDFHeart rate variability biofeedback in a global study of the most common coherence frequencies and the impact of emotional states.
Sci Rep
January 2025
HeartMath Institute, Boulder Creek, CA, 95006, USA.
This global study analyzed data from the largest dataset ever studied in the Heart Rate Variability (HRV) biofeedback field, comprising 1.8 million user sessions collected from users of a mobile app during 2019 and 2020. We focused on HRV Coherence, which is linked to improved emotional stability and cognitive function.
View Article and Find Full Text PDFPifithrin-μ sensitizes mTOR-activated liver cancer to sorafenib treatment.
Cell Death Dis
January 2025
Department of Organ Transplantation and Hepatobiliary Surgery, Key Laboratory of Organ Transplantation of Liaoning Province, The First Hospital of China Medical University, Shenyang, China.
TSC2, a suppressor of mTOR, is inactivated in up to 20% of HBV-associated liver cancer. This subtype of liver cancer is associated with aggressive behavior and early recurrence after hepatectomy. Being the first targeted regimen for advanced liver cancer, sorafenib has limited efficacy in HBV-positive patients.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!