Hepatic drug conjugation/deconjugation systems in hepatosplenic schistosomiasis.

Biochem Pharmacol

Pharmacology Department, Faculty of Medicine, Assiut University, Cairo, Egypt.

Published: October 1990

The biotransformation capacity of the liver is altered in hepatosplenic schistosomiasis being more in favor of deconjugation pathways. These alterations should be considered when xenobiotics are administered and in studies of hepatic toxicity and carcinogenicity.

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http://dx.doi.org/10.1016/0006-2952(90)90375-uDOI Listing

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