The purpose of this study was to report the imaging manifestations of tumor associated with PNP. Imaging features of abdominal tumor associated with PNP in 6 cases were retrospectively analyzed. Patients were given PET/CT (n = 1) or multidetector CT (n = 5) examination. Six cases of PNP were associated with hyaline-vascular type Castleman's disease. Calcification was revealed in 2 cases. One case showed heterogeneous FDG uptake on PET. Among the 5 cases receiving a dynamic enhanced CT scan, inhomogeneous marked enhancement (n = 3) or moderate enhancement (n = 2) with hypo-attenuation areas of patchy shape were presented in the arterial phase. Three cases showed persistent enhancement in equilibrium and delayed phases, and intratumoral hypo-attenuation areas which pathologically proved to be an abundance of fibrotic components which gradually disappeared. PNP is a relatively rare special type of pemphigus, with distinctive clinical and pathological manifestations. Imaging examination plays important role in the detection and qualitative diagnosis of abdominal tumors associated with PNP.

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http://dx.doi.org/10.1684/ejd.2010.1187DOI Listing

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