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Hereditary angioedema in children: Review and practical perspective for clinical management.

Pediatr Allergy Immunol

December 2024

French National Reference Center for Angioedema (CREAK), Center of Excellence and Reference (ACARE), Internal Medicine Department, Grenoble Alpes University Hospital, Grenoble, France.

Background: Hereditary angioedema (HAE) in children has specific features and requires multidisciplinary management.

Methods: We performed a literature search and underwent in-depth discussions to provide practical tools for physicians.

Results: HAE is a rare, life-threatening genetic disorder.

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A systematic review of the clinicopathological characteristics of oral leiomyomatous hamartoma.

World J Surg Oncol

December 2024

Department of Research Analytics, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, 600 077, India.

Article Synopsis
  • Oral leiomyomatous hamartoma (OLH) is a benign overgrowth of smooth muscle tissue that can occur in various locations in the oral cavity.
  • The systematic review analyzed 55 studies involving 66 subjects, revealing that OLH lesions typically presented firm consistency, average size of 1.20 cm, and were often found on the tongue or maxilla, with surgical excision being the primary treatment method.
  • Despite its rarity, OLH is important for differential diagnosis in young patients with oral lesions, given its distinct clinicopathological features identified in the reviewed literature.
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Bleeding disorder in a Holstein calf comparable to bovine neonatal pancytopenia.

Aust Vet J

November 2024

Rochester Veterinary Practice, Rochester, Victoria, Australia.

The clinical findings associated with a bleeding disorder, suspected to be an immune mediated pathogenesis comparable to bovine neonatal pancytopenia (BNP), in a 14-day-old Holstein calf are summarised. The clinical examination, clinical laboratory findings, treatment, postmortem findings and referral laboratory diagnostics are reported and discussed in relation to existing knowledge of bleeding disorders in cattle. Veterinary attention was required for a twin 14-day-old Holstein calf that was lethargic, weak and had pale mucous membranes.

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Tongue-base cysts, which are occasionally categorized as vallecular cysts, are a rare yet potentially life-threatening cause of stridor in pediatric patients. Studies reporting the use of point-of-care ultrasound (POCUS) to identify tongue-base cysts are lacking. We present the case series of four infants in whom tongue-base cysts were detected using neck POCUS.

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Background: Premature infants commonly encounter difficulties with oral feeding, a complication that extends hospital stays, affects infants' quality of life, and imposes substantial burdens on families and society. Enhancing preterm infants' oral feeding skills and facilitating their transition from parenteral or nasal feeding to full oral feeding pose challenges for neonatal intensive care unit (NICU) healthcare professionals. Research indicates that oral motor interventions (OMIs) can enhance preterm infants' oral feeding capabilities and expedite the transition from feeding initiation to full oral feeding.

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