AI Article Synopsis
- Castleman's disease is a rare condition characterized by abnormal lymph node growth, often linked to other diseases, including autoimmune disorders and cancers.
- A 72-year-old woman with myasthenia gravis underwent surgery for a tumor in her chest, which led to the diagnosis of hyaline vascular-type Castleman's disease, along with a rare cancer called follicular dendritic cell sarcoma.
- Currently, the patient is receiving treatment with medications to manage her myasthenia gravis.
Article Abstract
Castleman's disease is an atypical lymphoproliferative disorder of unknown etiology, which might be associated with various clinical conditions, including autoimmune diseases and malignant neoplasms. We report the case of a 72-year-old female patient who was referred to the thoracic surgery department of Getúlio Vargas University Hospital, in the city of Manaus, Brazil, for the resection of a posterior mediastinal tumor. Three months prior, the patient had been admitted to the ICU with signs of severe dyspnea, at which time she was diagnosed with myasthenia gravis. After the resection of the mediastinal tumor, the histopathological examination revealed hyaline vascular-type Castleman's disease, complicated by follicular dendritic cell sarcoma. At this writing, the patient was being treated with an anticholinesterase agent and corticosteroids for the control of myasthenia gravis.
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| http://dx.doi.org/10.1590/s1806-37132010000600020 | DOI Listing |
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