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http://dx.doi.org/10.1684/ejd.2010.1170DOI Listing

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Article Synopsis
  • Dermatologic issues have become more prevalent among oncohematologic patients, prompting a study to assess their incidence and variety in a Hematology Department.
  • The study involved 60 patients and identified 73 skin manifestations, categorizing them into specific, immune-mediated, and immunosuppression-related lesions.
  • Findings highlighted that immune-mediated manifestations were most common, particularly in leukemia patients, emphasizing the need for collaboration between hematologists and dermatologists for effective diagnosis and management.
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Eight cases of adult T-cell leukaemia/lymphoma (ATLL) with cutaneous involvement were studied. The clinical and histological features of these cases were recorded and immunohistochemistry carried out using a panel of monoclonal antibodies to T-cell differentiation antigens. Patients with ATLL showed distinct differences from patients with mycosis fungoides (MF) and Sézary syndrome (SS).

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Schistosomiasis mansoni, a potentially severe disease that victimizes an appreciable number of US citizens in this hemisphere, shows cutaneous changes corresponding to various stages in the life cycle of the causative parasite within its definitive host. A transient pruritus or dermatitis, probably irritative, characterizes the stage of cercarial penetration. Urticaria, periorbital edema, and rarely a purpuric eruption may occur four to six weeks later, shortly after oviposition by adult worms, probably as an expression of hypersensitivity to ova and their products.

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